Grubb B P, Thant M
Am J Med Sci. 1986 Dec;292(6):393-4. doi: 10.1097/00000441-198612000-00012.
This case report describes a 76-year-old white woman who was found to have ovarian cancer and underwent chemotherapy with hexamethylmelamine. After 34 months of therapy, she developed an acute myelocytic leukemia. Although commonly reported as a side effect of alkylating agents, this is believed to be the first reported case of an acute nonlymphocytic leukemia associated with hexamethylmelamine use.
本病例报告描述了一名76岁的白人女性，她被诊断患有卵巢癌，并接受了六甲蜜胺化疗。治疗34个月后，她患上了急性髓细胞白血病。尽管急性髓细胞白血病通常被报道为烷化剂的副作用，但据信这是首例与使用六甲蜜胺相关的急性非淋巴细胞白血病报告病例。
