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阳离子对蛙舌水纤维Ca2+反应的抑制作用。

Inhibitory effects of cations on the Ca2+ response of water fibers in the frog tongue.

作者信息

Kitada Y

出版信息

Jpn J Physiol. 1978;28(4):413-22. doi: 10.2170/jjphysiol.28.413.

DOI:10.2170/jjphysiol.28.413
PMID:309963
Abstract

The effects of various cations on water fibers in the frog (Rana catesbeiana) tongue were investigated. The following results were obtained. 1. Water fibers responded well to Ca2+ and Sr2+. 2. SO2-(4) did not inhibit the Ca2+ response. Cl- at high concentrations had an inhibitory effect on the response to high Ca2+ stimulation. However, when the Ca2+ concentration was low, Cl- did not induce any inhibition. Therefore, low Ca2+ stimulation (0.1 mM CaCl2) was used to examine the inhibitory effect of cation. 3. MgCl2 and MgSO4 strongly inhibited the response to low Ca2+ stimulation. The inhibition by Mg salts was not caused by anion but by Mg2+. 4. The Ca2+ response was inhibited by various cations. The order of the inhibitory effects of cations was as follows: La3+ greater than Mn2+ = Mg2+ greater than or equal to Ni2+ greater than Co2+ greater than monovalent cations (Na+, K+, NH4+ and choline+). 5. The Sr2+ response, as well as the Ca2+ response, was inhibited by Na+ and Mg2+.

摘要

研究了多种阳离子对牛蛙(Rana catesbeiana)舌部水纤维的影响。得到以下结果:1. 水纤维对Ca2+和Sr2+反应良好。2. SO2-(4)不抑制Ca2+反应。高浓度的Cl-对高Ca2+刺激的反应有抑制作用。然而,当Ca2+浓度较低时,Cl-不会产生任何抑制作用。因此,采用低Ca2+刺激(0.1 mM CaCl2)来检测阳离子的抑制作用。3. MgCl2和MgSO4强烈抑制对低Ca2+刺激的反应。镁盐的抑制作用不是由阴离子引起的,而是由Mg2+引起的。4. Ca2+反应受到各种阳离子的抑制。阳离子抑制作用的顺序如下:La3+>Mn2+ = Mg2+≥Ni2+>Co2+>单价阳离子(Na+、K+、NH4+和胆碱+)。5. Sr2+反应以及Ca2+反应均受到Na+和Mg2+的抑制。

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