血友病个性化预防的临床实践：来自两大洲的经验与益处实例
Clinical practice of personalized prophylaxis in hemophilia: Illustrations of experiences and benefits from two continents.
作者信息
Jackson Shannon, Santoro Cristina, Gue Deborah, Ferretti Antonietta, Gaglioti Domenico, Squire Sandra, Mazzucconi Maria Gabriella, Hermans Cedric
机构信息
Inherited Bleeding Disorders Program of BC - Adult Division St. Paul's Hospital Vancouver British Columbia Canada.
Division of Hematology, Department of Medicine University of British Columbia Vancouver British Columbia Canada.
出版信息
Clin Case Rep. 2019 Feb 20;7(4):689-694. doi: 10.1002/ccr3.2021. eCollection 2019 Apr.
Abstract
These cases of people with hemophilia (PWH) illustrate the importance of understanding the patient's expectations and desires and adapting treatment to meet these needs, in addition to traditional clinical targets. Population PK modeling and FVIII products with improved PK profiles provide the opportunity to individualize care and improve long-term outcomes.
摘要
这些血友病患者（PWH）的案例表明，除了传统的临床指标外，了解患者的期望和需求并调整治疗以满足这些需求非常重要。群体药代动力学建模以及具有改善药代动力学特征的FVIII产品为个性化治疗和改善长期预后提供了机会。
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本文引用的文献
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Patient powered prophylaxis: A 12-month study of individualized prophylaxis in adults with severe haemophilia A.患者主导的预防治疗：一项为期 12 个月的重度 A 型血友病成人个体化预防治疗研究。
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Joining the patient on the path to customized prophylaxis: one hemophilia team explores the tools of engagement.与患者一同踏上定制预防之路：一个血友病治疗团队探索参与工具。
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Tailoring care to haemophilia patients' needs: which specialty and when?根据血友病患者的需求提供个性化护理：由哪个专科以及何时提供？
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Pharmacokinetic properties of BAY 81-8973, a full-length recombinant factor VIII.全长重组因子VIII BAY 81-8973的药代动力学特性
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Guidance on the dental management of patients with haemophilia and congenital bleeding disorders.血友病和先天性出血性疾病患者的牙科治疗指南。
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