健康成年猫群体泪液分泌昼夜节律的初步评估。
Pilot evaluation of the circadian rhythm of tear production in a population of healthy adult cats.
作者信息
Faghihi Houman, Rajaei Seyed Mehdi, Ansari Mood Manely, Williams David L
机构信息
Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Ophthalmology Section, Negah Veterinary Centre, Tehran, Iran.
出版信息
Vet Ophthalmol. 2019 Nov;22(6):916-920. doi: 10.1111/vop.12673. Epub 2019 Apr 17.
OBJECTIVES
The purpose of this study was to determine if a circadian rhythm exists in Schirmer's tear test (STT-1) values in a group of healthy adult cats.
ANIMALS STUDIED
Twenty adult neutered Domestic Short-haired cats (DSH) were used in the study.
PROCEDURES
Tear production was measured with the Schirmer tear test (STT-1) at 12 different time points over a 48-hour period.
RESULTS
A significant difference (approximately 4.3 mm/min) was noted between STT-1 values measured between 4 pm (lowest) and 12 am (highest) on both day 1 (P = 0.02) and day 2 (P = 0.01), and substantial variation in STT-1 values was observed at different times during the 48-hour period.
CONCLUSIONS
Significant variation in mean STT-1 values demonstrates that there is a circadian rhythm in tear production in cats and thus shows the importance of taking the time of day into account when measuring STT-1 in cats.
目的
本研究旨在确定一组健康成年猫的泪液分泌试验（STT-1）值是否存在昼夜节律。
研究动物
本研究使用了20只成年去势家养短毛猫（DSH）。
实验步骤
在48小时内的12个不同时间点，用泪液分泌试验（STT-1）测量泪液分泌量。
结果
在第1天（P = 0.02）和第2天（P = 0.01），下午4点（最低）和凌晨12点（最高）测量的STT-1值之间存在显著差异（约4.3毫米/分钟），并且在48小时期间的不同时间观察到STT-1值有很大变化。
结论
平均STT-1值的显著变化表明猫的泪液分泌存在昼夜节律，因此表明在测量猫的STT-1时考虑一天中的时间很重要。
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