Bawa-Allah Abdulraheem B, Mashao Mercy M, Nyundu Thamsanqa F, Phukubje Edgar M, Mlambo Bongubuhle W, Ngema Mandisa V, Nkosi Brian G, Maseko Muzi J
South African Hypertension and Diet Study, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Blood Press Monit. 2019 Jun;24(3):103-109. doi: 10.1097/MBP.0000000000000376.
We aimed to establish reference values for 24 h ambulatory blood pressure (ABP) monitoring in an African community.
We randomly recruited 1219 participants of African ancestry from Soweto, a township in Johannesburg. Twenty-four hour ABP was measured using ABP monitors (model 90207; Spacelab). Complete 24 h ABP measurements from 530 healthy participants with a mean age of 38 were used to determine thresholds.
Twenty-four hour, daytime and night-time systolic and diastolic BP increased significantly with age. The 95th prediction bands of this relation at age 38 years were ∼135/85 mmHg for 24 h, 140/90 mmHg for daytime and 130/80 mmHg for night-time ABP values, respectively. These thresholds and absolute ABP values are similar to those observed in individuals of other demographics. These thresholds increase with age by an average of 1.5 mmHg with each decade's increase in age.
Pending authentication in prospective outcome-based studies, these values might be considered preliminary thresholds to diagnose hypertension in individuals of African descent.
我们旨在建立非洲某社区24小时动态血压（ABP）监测的参考值。
我们从约翰内斯堡的一个城镇索韦托随机招募了1219名非洲裔参与者。使用ABP监测仪（型号90207；太空实验室）测量24小时ABP。来自530名平均年龄为38岁的健康参与者的完整24小时ABP测量值用于确定阈值。
24小时、日间和夜间的收缩压和舒张压均随年龄显著升高。在38岁时，这种关系的第95百分预测区间分别为：24小时ABP约为135/85 mmHg，日间为140/90 mmHg，夜间为130/80 mmHg。这些阈值和绝对ABP值与其他人口统计学个体中观察到的相似。这些阈值随年龄每增加十岁平均升高1.5 mmHg。
在基于前瞻性结果的研究进行验证之前，这些值可被视为诊断非洲裔个体高血压的初步阈值。
