Wallbach M, Tampe B, Dihazi H, Koziolek M J
Klinik für Nephrologie und Rheumatologie, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.
Internist (Berl). 2019 Jun;60(6):578-586. doi: 10.1007/s00108-019-0602-y.
In addition to the early detection of an acute kidney injury (AKI), several problems or questions have to be addressed. These include the identification of the etiology, the severity (functional or structural), the prognosis (recovery or transition to chronic renal failure), the course of the disease (dialysis or not), and the identification of specific treatment options for AKI. The following article provides an overview of established and new AKI biomarkers as well as an outlook on the potential of future biomarker-associated models of AKI.
除了急性肾损伤（AKI）的早期检测外，还必须解决几个问题。这些问题包括病因的确定、严重程度（功能性或结构性）、预后（恢复或转变为慢性肾衰竭）、疾病进程（是否进行透析）以及AKI特定治疗方案的确定。以下文章概述了已确立的和新的AKI生物标志物，并展望了未来与生物标志物相关的AKI模型的潜力。
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