Department of Biochemistry and Clinical Chemistry, Medical University of Warsaw, Warsaw, Poland.
Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):2950-2959. doi: 10.26355/eurrev_201904_17575.
Evidence from epidemiological and clinical studies strongly suggest that young women in the preconception period are a group at risk for thyroid disorders which may lead to further aggravation of pre-existing chronic thyroid disease and complications during pregnancy.
This paper is a literature review focusing on articles published in English between 2014-2017 searched in Medline database using terms 'young women', 'subclinical hyperthyroidism', 'subclinical hypothyroidism', 'nonthyroidal illness syndrome', 'obesity', 'depression'.
Clinical assessment of young female patient including that of obtaining full medical history with a focus on the perceived changes in appearance, psychological symptoms and menstrual irregularities supported by laboratory tests indicative of metabolic status and characteristic changes in thyroid functions, may be the key to well-reasoned and justified individual therapeutic decisions.
流行病学和临床研究的证据强烈表明，处于孕前阶段的年轻女性是甲状腺疾病的高危人群，这可能导致已存在的慢性甲状腺疾病进一步恶化，并在怀孕期间出现并发症。
本文是一篇文献综述，重点关注了 2014-2017 年间在 Medline 数据库中使用“年轻女性”、“亚临床甲状腺功能亢进症”、“亚临床甲状腺功能减退症”、“非甲状腺疾病综合征”、“肥胖症”、“抑郁症”等术语发表的英文文章。
对年轻女性患者的临床评估，包括详细的病史采集，重点关注患者感知到的外貌变化、心理症状和月经不规律，这些都可以通过实验室检查来支持，以评估代谢状态和甲状腺功能的特征变化，这可能是做出合理和有依据的个体化治疗决策的关键。
