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经导管栓塞明胶海绵颗粒治疗医源性冠状动脉穿孔的急救处理——技术描述。

Emergency treatment of iatrogenic coronary perforation by transcatheter embolization with gelatin sponge particles-Description of technique.

机构信息

Department of Cardiology, Poznań University of Medical Sciences, Poznan, Poland.

Department of Interventional Cardiology, HCP Medical Center Poznań, Poznan, Poland.

出版信息

Catheter Cardiovasc Interv. 2019 Aug 1;94(2):223-226. doi: 10.1002/ccd.28291. Epub 2019 Apr 19.

DOI:10.1002/ccd.28291
PMID:31002207
Abstract

Coronary artery perforation (CAP) is a rare but potentially life-threatening complication of percutaneous coronary intervention (PCI) that requires prompt diagnosis and effective treatment. Importantly, dynamic advances in interventional cardiology reflected by the increasing percentage of more challenging PCIs performed in more complex lesions have resulted in significant changes in CAPs pattern. Herein, we describe a technique and present a case report of CAP that occurred during percutaneous recanalization of the occluded restenotic right coronary artery (RCA) successfully treated with transcatheter embolization using gelatin sponge particles prepared on-site. The patient underwent coronary angiography with a subsequent attempt to open chronically occluded RCA. During the procedure, a guidewire was inadvertently positioned outside the arterial bed resulting in type III CAP. After unsuccessful prolonged balloon inflations as well as an anticoagulation reversal, embolization of the RCA with gelatin sponge particles as an ultima ratio treatment was performed. Sponge particles were prepared on-site by the operator, by cutting gelatin sponge used for wound healing. The procedure resulted in a total occlusion of the RCA and significant clinical improvement. The patient did not require pericardiocentesis and was discharged from the hospital after 10 days of an uneventful postprocedural course. The described technique is an easy and effective method of guidewire-related CAPs treatment in whom stent grafts cannot be implanted. Noteworthy, the technique can be applied in most cath labs as it utilizes a widely available gelatin sponge and does not require any specific expertise.

摘要

冠状动脉穿孔 (CAP) 是经皮冠状动脉介入治疗 (PCI) 的一种罕见但潜在危及生命的并发症,需要及时诊断和有效治疗。重要的是,介入心脏病学的动态进展反映在越来越多的复杂病变中进行更具挑战性的 PCI 的百分比增加,导致 CAP 模式发生了重大变化。在此,我们描述了一种技术,并报告了一例在经皮闭塞再狭窄右冠状动脉 (RCA) 再通过程中发生的 CAP 病例,该病例成功地使用现场制备的明胶海绵颗粒进行经导管栓塞治疗。患者接受了冠状动脉造影检查,随后试图开通慢性闭塞的 RCA。在该过程中,导丝不慎位于动脉床外,导致 III 型 CAP。在多次延长球囊充气失败以及抗凝逆转后,作为最后手段,对 RCA 进行了明胶海绵颗粒栓塞治疗。海绵颗粒由术者现场制备,通过切割用于伤口愈合的明胶海绵。该操作导致 RCA 完全闭塞,并显著改善了临床症状。患者无需进行心包穿刺,在无并发症的术后 10 天后出院。所描述的技术是一种简单有效的治疗与导丝相关的 CAP 的方法,对于无法植入支架的患者尤其适用。值得注意的是,该技术可以在大多数导管室应用,因为它使用了广泛可用的明胶海绵,且不需要任何特定的专业知识。

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