Mirandola Daniela, Muraca Maria Grazia, Sgambati Eleonora, Manetti Mirko, Marini Mirca
Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, 50134 Florence, Italy.
Oncological Network, Prevention and Research Institute (ISPRO), 50139 Florence, Italy.
J Clin Med. 2019 Apr 18;8(4):531. doi: 10.3390/jcm8040531.
Physical activity (PA) interventions can improve physical functioning, treatment-related symptoms and quality of life (QoL) in cancer survivors. Most investigations have been conducted in breast cancer survivors, while studies on PA interventions in gynecological cancer survivors are scant. Here, we report for the first time the possible benefits of a structured PA pathway (i.e., eight weeks of adapted PA followed by twelve weeks of adapted fitness) on physical side effects, pain and QoL in an uncommon case of survivorship of both primary breast and gynecological cancers. For this purpose, a 69-year-old woman was assessed by functional test battery (shoulder-arm mobility, range of motion, back flexibility) at baseline and after the structured PA pathway. QoL and surgical shoulder, back and lower limb pain intensity were evaluated by Short Form-12 (SF-12) and numerical rating scale questionnaires, respectively. Lower limb circumference was also assessed. Improvement in upper limb function, reduction of lower limb edema and pain perception, as well as an increase in overall QoL were achieved after the completion of structured PA intervention. Our findings suggest that a PA intervention tailored to individual characteristics may represent an effective countermeasure to reduce post-treatment functional disability and pain, and thus to improve QoL in breast and gynecologic cancer survivors.
体育活动(PA)干预可以改善癌症幸存者的身体机能、治疗相关症状和生活质量(QoL)。大多数研究是在乳腺癌幸存者中进行的,而关于妇科癌症幸存者PA干预的研究很少。在此,我们首次报告了一种结构化PA方案(即八周适应性PA,随后是十二周适应性健身)对一名同时患有原发性乳腺癌和妇科癌症的罕见幸存者的身体副作用、疼痛和生活质量的可能益处。为此,对一名69岁女性在基线时以及结构化PA方案实施后通过功能测试组合(肩臂活动度、活动范围、背部柔韧性)进行评估。生活质量以及手术引起的肩部、背部和下肢疼痛强度分别通过简明健康调查问卷(SF-12)和数字评分量表问卷进行评估。还评估了下肢周长。在完成结构化PA干预后,上肢功能得到改善,下肢水肿和疼痛感知减轻,总体生活质量提高。我们的研究结果表明,针对个体特征量身定制的PA干预可能是减少治疗后功能残疾和疼痛、从而改善乳腺癌和妇科癌症幸存者生活质量的有效对策。