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全身麻醉与椎管内麻醉用于翻修全膝关节置换术:并发症发生率是否不同?

General vs Spinal Anesthesia for Revision Total Knee Arthroplasty: Do Complication Rates Differ?

机构信息

Department of Orthopaedic Surgery, Emory University, Atlanta, GA.

出版信息

J Arthroplasty. 2019 Jul;34(7):1417-1422. doi: 10.1016/j.arth.2019.03.048. Epub 2019 Mar 28.

Abstract

BACKGROUND

The incidence of both primary total knee arthroplasty (TKA) and revision TKA is increasing. Data from primary arthroplasty patients suggest a risk reduction with the use of spinal anesthesia when compared with general anesthesia. However, the same relationship has not been examined in the revision knee arthroplasty patient.

METHODS

This is a retrospective cohort study using the American College of Surgeons-National Surgical Quality Improvement database. Patients undergoing revision TKA with either spinal or general anesthesia were identified from the database. Baseline characteristics were compared, and ultimately patients were matched using coarsened exact matching. Multivariate analysis was then performed on matched cohorts controlling for baseline patient and operative characteristics. This model was used to look for any differences in rates of complications, operative time, length of stay, and readmission.

RESULTS

Patients undergoing revision TKA with general anesthesia had increased risk of several postoperative complications, even after controlling for baseline patient characteristics. Specifically, there were significantly increased rates of the following: unplanned readmission (OR = 1.43, 95% confidence interval [CI] = 1.18-1.72, P < .001), nonhome discharge (OR = 1.60, 95% CI = 1.46-1.76, P < .001), transfusion (OR = 1.63, 95% CI = 1.41-1.88, P < .001), deep surgical site infection (OR = 1.43, 95% CI = 1.01-2.03, P = .043), and extended length of stay (OR = 1.22, 95% CI = 1.11-1.34, P < .001). General anesthesia was additionally associated with increased operative time.

CONCLUSION

General anesthesia is associated with increased risk of numerous postoperative complications in patients undergoing revision TKA. This study is retrospective in nature, and while causality cannot be definitively determined, the results suggest that spinal anesthesia is preferential to general anesthesia in the revision TKA patient.

摘要

背景

初次全膝关节置换术(TKA)和翻修 TKA 的发病率都在增加。来自初次关节置换患者的数据表明,与全身麻醉相比,使用椎管内麻醉可降低风险。然而,这种关系在翻修膝关节置换患者中尚未得到检验。

方法

这是一项使用美国外科医师学会-国家手术质量改进数据库的回顾性队列研究。从数据库中确定了接受翻修 TKA 且使用椎管内麻醉或全身麻醉的患者。比较了基线特征,最终通过粗化精确匹配对患者进行匹配。然后,在控制基线患者和手术特征的情况下,对匹配队列进行多变量分析。该模型用于寻找并发症、手术时间、住院时间和再入院率的任何差异。

结果

即使在控制了基线患者特征后,接受全身麻醉的翻修 TKA 患者发生多种术后并发症的风险增加。具体来说,以下并发症的发生率显著增加:计划外再入院(OR=1.43,95%置信区间[CI]=1.18-1.72,P<.001)、非家庭出院(OR=1.60,95%CI=1.46-1.76,P<.001)、输血(OR=1.63,95%CI=1.41-1.88,P<.001)、深部手术部位感染(OR=1.43,95%CI=1.01-2.03,P=.043)和延长住院时间(OR=1.22,95%CI=1.11-1.34,P<.001)。全身麻醉还与手术时间延长有关。

结论

全身麻醉与翻修 TKA 患者发生多种术后并发症的风险增加有关。本研究为回顾性研究,虽然不能确定因果关系,但结果表明椎管内麻醉在翻修 TKA 患者中优于全身麻醉。

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