Institute of Psychiatry, Psychology and Neuroscience (HS), King's College London, London.
Department of Medicine and Optometry, Linnaeus University, Kalmar, Sweden; Low Vision and Visual Rehabilitation Lab, Department and Center of Physics - Optometry and Vision Science, University of Minho, Braga, Portugal.
Am J Geriatr Psychiatry. 2019 Aug;27(8):755-773. doi: 10.1016/j.jagp.2019.03.001. Epub 2019 Mar 7.
To review the current literature on psychosocial and psychological interventions to prevent and treat depression and anxiety in patients with age-related macular degeneration (AMD).
The authors conducted a systematic review of literature evaluating psychosocial and psychological interventions for depression and anxiety in patients with AMD. Primary searches of PubMed, Cochrane library, EMBASE, Global Health, Web of Science, EBSCO, and Science Direct were conducted to include all articles published up to April 21, 2018.
Of a total of 398 citations retrieved, the authors selected 12 eligible studies published between 2002 and 2016. The authors found nine randomized controlled trials (RCT), and three non-randomized intervention (NRI) studies. RCT studies suggested that interventions using group self-management techniques and individual behavioral activation plus low vision rehabilitation can be effective to treat and prevent depression in patients with AMD, and one study suggested that a stepped-care intervention using cognitive-behavioral techniques can be effective to manage anxiety and depression over time. NRI studies highlighted a positive effect of self-help and emotion-focused interventions to reduce depression.
Clinical practice with patients with AMD can rely on some tailored cognitive-behavioral therapeutic protocols to improve patients' mental health, but further clinical trials will generate the necessary evidence-based knowledge to improve those therapeutic techniques and offer additional tailored interventions for patients with AMD.
综述与年龄相关性黄斑变性（AMD）患者抑郁和焦虑的预防和治疗相关的社会心理和心理干预的现有文献。
作者对评估 AMD 患者抑郁和焦虑的社会心理和心理干预的文献进行了系统评价。主要检索了 PubMed、Cochrane 图书馆、EMBASE、全球健康、Web of Science、EBSCO 和 Science Direct，以纳入截至 2018 年 4 月 21 日发表的所有文章。
共检索到 398 条引文，作者选择了 2002 年至 2016 年期间发表的 12 项合格研究。作者发现了 9 项随机对照试验（RCT）和 3 项非随机干预（NRI）研究。RCT 研究表明，使用团体自我管理技术和个体行为激活加低视力康复的干预措施可以有效治疗和预防 AMD 患者的抑郁，一项研究表明，使用认知行为技术的阶梯式护理干预可以有效管理随时间推移的焦虑和抑郁。NRI 研究强调了自助和情绪焦点干预对减轻抑郁的积极影响。
可以依靠一些量身定制的认知行为治疗方案为 AMD 患者提供临床实践，以改善患者的心理健康，但需要进一步的临床试验来生成必要的循证知识，以改进这些治疗技术并为 AMD 患者提供额外的量身定制的干预措施。
