Lin Ying, Chang Yu, Lin Yen-Chun, Lou Meei-Fang
National Taiwan University.
Oncol Nurs Forum. 2019 May 1;46(3):E86-E97. doi: 10.1188/19.ONF.E86-E97.
Nurses taking measures regarding the safe handling of hazardous drugs (HDs) can reduce their risk of exposure and environmental contamination. However, the findings of studies examining factors influencing the use of HD safe handling precautions by nurses have been inconsistent.
An integrative review of the Embase® and Scopus® electronic databases was performed.
The search strategy yielded 907 articles. Ten quantitative studies and two qualitative studies met the inclusion criteria. The Health Evidence Bulletin Wales checklist was used to evaluate the quality of the articles.
The outcome variables were categorized as engineering controls, work practice controls, and personal protective equipment (PPE) use. The frequency of PPE use was measured as an outcome variable in all reviewed studies. Associated factors were based on the behavioral-diagnostic model. Perceived barriers to PPE use, perceived safety climate, and workload were common factors related to the use of safety precautions.
Nurses should proactively obtain information about the safe handling of HDs and share their perceptions and experiences of it with their colleagues. Managers should actively construct a safe environment by adopting high reliability principles and provide nurses with sufficient and easy-to-use PPE.
采取措施安全处理高危药物（HDs）的护士可以降低自身暴露风险和环境污染风险。然而，关于影响护士采取HDs安全处理预防措施的因素的研究结果并不一致。
对Embase®和Scopus®电子数据库进行了综合检索。
检索策略共得到907篇文章。十项定量研究和两项定性研究符合纳入标准。使用威尔士健康证据公告清单来评估文章质量。
结果变量分为工程控制、工作实践控制和个人防护装备（PPE）使用情况。在所有纳入研究中，PPE的使用频率作为结果变量进行测量。相关因素基于行为诊断模型。PPE使用的感知障碍、感知安全氛围和工作量是与安全预防措施使用相关的常见因素。
护士应主动获取有关HDs安全处理的信息，并与同事分享自己对其的看法和经验。管理人员应通过采用高可靠性原则积极营造安全环境，并为护士提供充足且易于使用的PPE。
