Vermeulen Karina M, Lopes Márcia M G D, Grilo Evellyn C, Alves Camila X, Machado Richele J A, Lais Lucia L, Brandão-Neto José, Vale Sancha H L
Postgraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Department of Nutrition, Federal University of Rio Grande do Norte, Natal, Brazil.
Food Nutr Res. 2019 Apr 10;63. doi: 10.29219/fnr.v63.1615. eCollection 2019.
Duchenne muscular dystrophy (DMD) is a disease characterized by progressive loss of functional muscle mass followed by changes in body composition.
This study aimed to describe and evaluate bioimpedance parameters in boys with DMD.
This cross-sectional, descriptive study investigated children and adolescents diagnosed with DMD. Age, weight, height, resistance, and reactance data were collected. Phase angle and bioelectrical impedance vector analysis were calculated based on resistance and reactance values.
We analyzed 43 boys aged between 2.7 and 19.8 years. Low-phase angle values were observed during the investigation of bioimpedance parameters. Bioelectrical impedance vector analysis showed that approximately 87% of the subjects presented vectors outside the tolerance ellipses, and only one patient presented vectors located within the 50% tolerance ellipse, indicating normally hydrated and a good body cell mass. Compared with the reference population, boys with DMD had lower levels of body cell mass.
Based on the evidence, compared with the reference population, patients with DMD had lower levels of body cell mass. This evidence points to bioimpedance parameters as useful tools for the nutritional evaluation and clinical management of patients with DMD.
杜氏肌营养不良症（DMD）是一种以功能性肌肉质量逐渐丧失并伴有身体成分改变为特征的疾病。
本研究旨在描述和评估DMD男孩的生物电阻抗参数。
这项横断面描述性研究对诊断为DMD的儿童和青少年进行了调查。收集了年龄、体重、身高、电阻和电抗数据。根据电阻和电抗值计算相位角和生物电阻抗矢量分析。
我们分析了43名年龄在2.7岁至19.8岁之间的男孩。在生物电阻抗参数调查期间观察到低相位角值。生物电阻抗矢量分析表明，约87%的受试者的矢量位于耐受椭圆之外，只有一名患者的矢量位于50%耐受椭圆内，表明水分正常且身体细胞质量良好。与参考人群相比，DMD男孩的身体细胞质量水平较低。
基于这些证据，与参考人群相比，DMD患者的身体细胞质量水平较低。这一证据表明生物电阻抗参数是用于DMD患者营养评估和临床管理的有用工具。
