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突尼斯莫纳斯提尔65岁以上女性的乳腺疾病

Breast diseases in women over the age of 65 in Monastir, Tunisia.

作者信息

Haddad Anis, Zoukar Olfa, Daldoul Amira, Bhiri Hanene, Wiem Khechine, Mhabrich Houda, Zaied Sonia, Faleh Raja

机构信息

Department of Gynecology and Obstetrics, El Omrane Hospital, Monastir, Tunisia.

Department of Oncology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.

出版信息

Pan Afr Med J. 2018 Oct 1;31:67. doi: 10.11604/pamj.2018.31.67.16105. eCollection 2018.

Abstract

As life expectancy is on the rise, it is predicted that a growing number of people will live beyond the age of 65 and therefore a higher number of elderly women will have breast diseases requiring significant health care and services. This study is aimed at investigating the characteristics, the treatment and outcomes of women older than 65 years old treated for breast diseases at our institution. This was a retrospective study covering the period from January 2003 to December 2011. It involved 92 patients aged over 65 and treated for breast disease in the Maternity Center of Monastir, Tunisia. The data included characteristics of patients and tumors, treatment and outcomes that were obtained through data extraction sheets. We reported a study of 92 women over the age of 65 of whom 77 women had malignant breast disease (83.6%) and 15 benign breast diseases (16.4%). Breast cancer was discovered at a mean age of 72.5 ± 6.6 years. Distant metastases were found in 5.3% of cases and infiltrative ductal carcinoma was detected in 85.7% of patients. Hormonal receptors were positive for estrogens in 64.7% of cases. Surgical treatment was performed in 73 patients and adjuvant treatment was prescribed for 67 women (86%). The complication rate was 16.6% among the 73 patients who underwent surgery. Benign breast diseases represented 16.3% of the mammary pathologies. Abscesses and fibrocystic mastopathy were the most frequent histological diagnoses. Despite great interest in geriatric gynecological pathology worldwide, many questions related to how optimally treat this patient population remain unanswered. In this study, a surgical treatment was performed in 94.8% of breast cancer patients and the complication rate was 16.6%.

摘要

随着预期寿命的增加,预计越来越多的人将活到65岁以上,因此将有更多老年女性患有需要大量医疗保健和服务的乳腺疾病。本研究旨在调查在我们机构接受乳腺疾病治疗的65岁以上女性的特征、治疗方法和治疗结果。这是一项回顾性研究,涵盖2003年1月至2011年12月期间。研究对象为突尼斯莫纳斯提尔妇产中心92例年龄超过65岁且接受乳腺疾病治疗的患者。数据包括通过数据提取表获得的患者和肿瘤特征、治疗方法和治疗结果。我们报告了一项对92名65岁以上女性的研究,其中77名女性患有恶性乳腺疾病(83.6%),15名患有良性乳腺疾病(16.4%)。乳腺癌的发现平均年龄为72.5±6.6岁。5.3%的病例发现有远处转移,85.7%的患者检测到浸润性导管癌。64.7%的病例中雌激素受体呈阳性。73例患者接受了手术治疗,67名女性(86%)接受了辅助治疗。在接受手术的73例患者中,并发症发生率为16.6%。良性乳腺疾病占乳腺病变的16.3%。脓肿和纤维囊性乳腺病是最常见的组织学诊断。尽管全球对老年妇科病理学非常关注,但许多关于如何最佳治疗这一患者群体的问题仍未得到解答。在本研究中,94.8%的乳腺癌患者接受了手术治疗,并发症发生率为16.6%。

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