Mahesan Arnold M, Sadek Seifeldin, Ramadan Hadi, Bocca Silvina, Paul Anthea B M, Stadtmauer Laurel
1Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, 700 W Olney Rd, Norfolk, VA 23507 USA.
2University of Ottawa, Ottawa, ON Canada.
Fertil Res Pract. 2019 Apr 10;5:5. doi: 10.1186/s40738-019-0057-9. eCollection 2019.
To assess knowledge and attitudes regarding elective oocyte cryopreservation among female undergraduate students (UG) and medical students (MS) in Eastern Virginia.
An anonymous cross-sectional study surveying female UG at a local university and MS at our academic medical center in May of 2017. The survey contained questions on demographic information, interest in fertility preservation, and knowledge about age related changes in fertility.
There were 74 of 102 female UG and 95 of 117 female MS who responded, for a response rate of 73 and 81% respectively. UG were significantly younger than MS (21.4 vs 26.8, < 0.001). Further, UG generally planned on conceiving at a younger age than MS (age 26-30 vs 31-35), and favored younger ages to consider oocyte cryopreservation (age 26-30 vs 31-35). Only a minority of both UG and MS were willing to undergo egg freezing at the current price of approximately $10,000 (15% vs 26% respectively, = 0.044). Moreover, 73% of students overall responded that they would be more likely to freeze oocytes if their employer paid. Notably, both UG and MS underestimated age of fertility decline.
Both UG and MS revealed a need for education on age-related changes in fertility. Most UG and MS would not undergo elective oocyte cryopreservation at the present cost but would consider it at a lower cost.
评估弗吉尼亚州东部女性本科生（UG）和医学生（MS）对选择性卵母细胞冷冻保存的知识和态度。
2017年5月，在当地一所大学对女性UG以及在我们学术医学中心对女性MS进行了一项匿名横断面研究调查。该调查包含有关人口统计学信息、生育力保存兴趣以及生育力与年龄相关变化知识的问题。
102名女性UG中有74名、117名女性MS中有95名做出回应，回应率分别为73%和81%。UG显著比MS年轻（21.4岁对26.8岁，<0.001）。此外，UG一般计划比MS在更年轻的年龄生育（26 - 30岁对31 - 35岁），并且倾向于在更年轻的年龄考虑卵母细胞冷冻保存（26 - 30岁对31 - 35岁）。只有少数UG和MS愿意以当前约10,000美元的价格接受卵子冷冻（分别为15%对26%，P = 0.044）。此外，总体上73%的学生回应称，如果雇主付费，他们更有可能冷冻卵母细胞。值得注意的是，UG和MS都低估了生育力下降的年龄。
UG和MS都表明需要接受关于生育力与年龄相关变化的教育。大多数UG和MS目前不会以现有的成本接受选择性卵母细胞冷冻保存，但会考虑以更低的成本进行。
