Azhar Hussain, Rizvi Syed Asad Hasan, Siddiqui Amna A, Siddiqui Fatima Q
Internal Medicine, Civil Hospital Karachi, Karachi, PAK.
Internal Hospital, Civil Hospital Karachi, Karachi, PAK.
Cureus. 2019 Feb 7;11(2):e4028. doi: 10.7759/cureus.4028.
Takayasu arteritis (TA) is a chronic inflammatory large-vessel vasculitis of the aorta and its major branches. It is a relatively rare disease, which presents with a wide spectrum of clinical features. Back pain is, however, rarely described to be a presenting symptom of TA. We report a case of a 28-year-old female with no known co-morbidity, who presented with back pain along with intermittent fever, dry cough, and significant weight loss. After an extensive inpatient workup, a computed tomography (CT) scan with contrast of chest and abdomen revealed evidence of vasculitis involving aorta, common carotid arteries, renal arteries, common iliac arteries as well as external and internal iliac arteries. A confirmatory CT abdominal aortography established the diagnosis of TA. The patient was treated with long-term oral corticosteroid therapy. Our case highlights that while assessing nonspecific back pain with elevated inflammatory parameters, particularly in young women, TA should be considered as one of the differential diagnoses.
高安动脉炎(TA)是一种累及主动脉及其主要分支的慢性炎症性大血管血管炎。它是一种相对罕见的疾病,临床表现多样。然而,背痛很少被描述为TA的首发症状。我们报告一例28岁女性,无已知合并症,以背痛伴间歇性发热、干咳和显著体重减轻就诊。经过全面的住院检查,胸部和腹部增强计算机断层扫描(CT)显示有血管炎累及主动脉、颈总动脉、肾动脉、髂总动脉以及髂内外动脉。腹部主动脉CT血管造影确诊为TA。该患者接受了长期口服糖皮质激素治疗。我们的病例强调,在评估伴有炎症指标升高的非特异性背痛时,尤其是在年轻女性中,应将TA列为鉴别诊断之一。