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柯萨奇病毒和腺病毒受体(CAR)在产前及成年大鼠嗅觉、肠道、胰腺、肝脏、卵巢和睾丸中的定位数据。

Data on localization of coxsackievirus and adenovirus receptor (CAR) in prenatal and adult rat olfactory, intestine, pancreas, liver, ovary, and testis.

作者信息

Chen Mo, Yoshida Saishu, Kato Takako, Kato Yukio

机构信息

Division of Life Science, Graduate School of Agriculture, Meiji University, Kawasaki, Kanagawa, 214-8571, Japan.

Institute for Endocrinology, Meiji University, Kawasaki, Kanagawa, 214-8571, Japan.

出版信息

Data Brief. 2019 Mar 1;24:103797. doi: 10.1016/j.dib.2019.103797. eCollection 2019 Jun.

Abstract

The data in the present article are related to the previous article entitled "Coxsackievirus and adenovirus receptor-positive cells compose the putative stem/progenitor cell niches in the marginal cell layer and parenchyma of the rat anterior pituitary" (M. Chen et al. 2013). The data describe the characteristic localization in the immature cells of the prenatal and adult tissues beyond the germ layer. Germ cells and the reproductive tissues of both sexes showed distinct intracellular polarities of CAR: apical, basolateral, and pericellular in the immature cells of the embryo and adult tissues. In addition, the data describe on localization of CAR in the methimazole-induced damage of olfactory epithelium tissue. The data show that the CAR-_immuno-positive cells at the apical side of the olfactory epithelium disappeared following methimazole treatment and reappeared in the regenerating stem/progenitor cells (positive for KI67 and E-cadherin) of the basal layer with basolateral expression.

摘要

本文中的数据与之前一篇题为《柯萨奇病毒和腺病毒受体阳性细胞构成大鼠垂体前叶边缘细胞层和实质中的假定干/祖细胞龛》(M. Chen等人,2013年)的文章相关。这些数据描述了胚层以外的产前和成年组织未成熟细胞中的特征性定位。生殖细胞和两性生殖组织在胚胎和成年组织的未成熟细胞中显示出柯萨奇病毒和腺病毒受体(CAR)明显的细胞内极性:顶端、基底外侧和细胞周围。此外,这些数据描述了CAR在甲巯咪唑诱导的嗅觉上皮组织损伤中的定位。数据显示,甲巯咪唑处理后,嗅觉上皮顶端侧的CAR免疫阳性细胞消失,并在基底层具有基底外侧表达的再生干/祖细胞(KI67和E-钙黏蛋白阳性)中重新出现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fc0/6458452/cd56cd3b4428/gr1.jpg

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