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爱尔兰卒中后第一年与跌倒相关的事件:多中心前瞻性FREESE队列研究结果

Falls-Related EvEnts in the first year after StrokE in Ireland: Results of the multi-centre prospective FREESE cohort study.

作者信息

Walsh Mary E, Galvin Rose, Williams David Jp, Harbison Joseph A, Murphy Sean, Collins Ronan, McCabe Dominick Jh, Crowe Morgan, Horgan N Frances

机构信息

School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland.

HRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland, Dublin, Ireland.

出版信息

Eur Stroke J. 2018 Sep;3(3):246-253. doi: 10.1177/2396987318764961. Epub 2018 Mar 16.

Abstract

INTRODUCTION

Falls are common post-stroke adverse events. This study aimed to describe the first-year falls incidence, circumstances and consequences among persons discharged home after stroke in Ireland, and to examine the association between potential risk factors and recurrent falls.

PATIENTS AND METHODS

Patients with acute stroke and planned home-discharge were recruited consecutively from five hospitals. Variables recorded pre-discharge included: age, stroke severity, co-morbidities, fall history, prescribed medications, hemi-neglect, cognition and functional independence (Barthel index). Falls were recorded with monthly diaries, and 6 and 12-month interviews. The association of pre-discharge factors with recurrent falls (>1 fall) was examined using univariable logistic regression.

RESULTS

A total of 128 participants (mean age = 68.6, SD = 13.3) were recruited; 110 completed the 12-month follow-up. The first-year falls incidence was 44.5% (95% CI = 35.1-53.6) with 25.6% falling repeatedly (95% CI = 18.5-34.4). Fallers experienced 1-18 falls (median = 2) and five reported fractures; 47% of fallers experienced at least one fall outdoors. Only 10% of recurrent fallers had bone health medication prescribed at discharge. Lower Barthel index scores (<75/100, RR = 4.38, 1.64-11.72) and psychotropic medication prescription (RR = 2.10, 1.13-3.91) were associated with recurrent falls.

DISCUSSION

This study presents prospectively collected information about falls circumstances. It was not powered for multivariable analysis of risk factors.

CONCLUSION

One-quarter of stroke survivors discharged to the community fall repeatedly and mostly indoors in the first year. Specific attention may be required for individuals with poor functional independence or those on psychotropic medication. Future falls-management research in this population should explore falls in younger individuals, outdoor as well as indoor falls and post-stroke bone health status.

摘要

引言

跌倒为常见的卒中后不良事件。本研究旨在描述爱尔兰卒中后出院回家的患者第一年的跌倒发生率、情况及后果,并探讨潜在危险因素与反复跌倒之间的关联。

患者与方法

从五家医院连续招募急性卒中且计划出院回家的患者。出院前记录的变量包括:年龄、卒中严重程度、合并症、跌倒史、处方药物、偏侧忽视、认知及功能独立性(巴氏指数)。通过每月的日记以及6个月和12个月的访谈记录跌倒情况。采用单变量逻辑回归分析出院前因素与反复跌倒(>1次跌倒)之间的关联。

结果

共招募128名参与者(平均年龄=68.6,标准差=13.3);110名完成了12个月的随访。第一年的跌倒发生率为44.5%(95%置信区间=35.1-53.6),25.6%的患者反复跌倒(95%置信区间=18.5-34.4)。跌倒患者经历了1-18次跌倒(中位数=2),5名报告有骨折;47%的跌倒患者至少有一次在户外跌倒。出院时只有10%的反复跌倒患者开具了骨骼健康药物。较低的巴氏指数评分(<75/100,相对风险=4.38,1.64-11.72)和精神药物处方(相对风险=2.10,1.13-3.91)与反复跌倒有关。

讨论

本研究前瞻性地收集了有关跌倒情况的信息。本研究未进行危险因素的多变量分析。

结论

四分之一出院至社区的卒中幸存者在第一年反复跌倒,且大多发生在室内。功能独立性差的个体或服用精神药物的个体可能需要特别关注。该人群未来的跌倒管理研究应探索年轻个体的跌倒情况、户外及室内跌倒情况以及卒中后的骨骼健康状况。

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