From the Cardiology Unit, P.O. San Filippo Neri, ASL Roma, Rome, Italy.
Intensive Care and Interventional Cardiology Unit, Azienda Ospedaliera "Bianchi Melacrino Morelli", Reggio Calabria, Italy.
Cardiol Rev. 2020 May/Jun;28(3):125-134. doi: 10.1097/CRD.0000000000000251.
Left ventricular noncompaction cardiomyopathy is a heart disease with relevant potential complications including heart failure, life-threatening arrhythmias, and embolic events. In order to prevent adverse outcomes, it is crucial to appropriately recognize and manage this cardiomyopathy. In this paper, we report the main clinical presentations and imaging modalities used for diagnosis, including echocardiography and magnetic resonance imaging. We highlight the role of a comprehensive functional cardiac evaluation and the possible prognostic implications of both systolic and diastolic dysfunction. Furthermore, we summarize clinical factors and imaging findings which have prognostic significance. Finally, we discuss the main management strategies based on phenotypic expressions which are aimed at treating symptoms and preventing complications.
左心室心肌致密化不全是一种伴有相关潜在并发症的心脏病，包括心力衰竭、威胁生命的心律失常和栓塞事件。为了预防不良后果，正确识别和管理这种心肌病至关重要。本文报告了主要的临床表现和用于诊断的影像学方法，包括超声心动图和磁共振成像。我们强调了全面的功能性心脏评估的作用，以及收缩和舒张功能障碍的可能预后意义。此外，我们总结了具有预后意义的临床因素和影像学发现。最后，我们根据表型表达讨论了主要的管理策略，旨在治疗症状和预防并发症。
