自 1998 年至 2017 年，丙型肝炎病毒感染的自发清除率增加了一倍。
Prevalence of Spontaneous Clearance of Hepatitis C Virus Infection Doubled From 1998 to 2017.
机构信息
Kaiser Permanente Antioch Medical Center, Antioch, California; Kaiser Permanente Walnut Creek Medical Center, Walnut Creek, California.
Division of Research, Kaiser Permanente Northern California, Oakland, California.
出版信息
Clin Gastroenterol Hepatol. 2020 Feb;18(2):511-513. doi: 10.1016/j.cgh.2019.04.035. Epub 2019 Apr 19.
Abstract
Strategic planning for hepatitis C virus (HCV) screening and treatment requires up-to-date information on the prevalence of HCV spontaneous clearance. Published estimates of HCV spontaneous clearance range from 15% to 60%. We conducted an observational study over 20 years to evaluate trends in the prevalence of HCV spontaneous clearance. Our goals were to estimate the proportion of HCV-antibody-positive patients who were viremic, and to identify factors associated with viremia, thus facilitating prediction of the number of patients needing treatment.
摘要
慢性丙型肝炎病毒 (HCV) 筛查和治疗的策略规划需要最新的 HCV 自发清除率数据。已发表的 HCV 自发清除率估计值范围为 15%至 60%。我们进行了一项为期 20 年的观察性研究，以评估 HCV 自发清除率的趋势。我们的目标是估计 HCV 抗体阳性患者中病毒血症的比例，并确定与病毒血症相关的因素，从而有助于预测需要治疗的患者数量。
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