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胎儿腹部内脏脂肪组织和皮下脂肪厚度能否用于准确估计胎儿体重?一项初步研究。

Can fetal abdominal visceral adipose tissue and subcutaneous fat thickness be used for correct estimation of fetal weight? A preliminary study.

作者信息

Köşüş Nermin, Köşüş Aydın

机构信息

a Department of ObGyn. Private Practice , Ankara , Turkey.

出版信息

J Obstet Gynaecol. 2019 Jul;39(5):594-600. doi: 10.1080/01443615.2018.1530971. Epub 2019 Apr 22.

Abstract

The aim of this study was to assess the accuracy of a new formula for the calculation of an estimated fetal weight (EFW) and to evaluate value of fetal visceral adipose tissue (VAT) and abdominal subcutaneous fat (SF) thickness on the prediction of birth weight. In this prospective study, fetal biometry, EFW, fetal VAT and SF thickness were measured in low-risk 37-41 gestational weeks pregnant women by ultrasonography. The linear regression analysis was performed to investigate the relationship between birth weight and obstetric measurements. It was found that the most important factors in the prediction of a birth weight were the abdominal circumference (AC), SF and VAT. The new formula for EFW was According to the Hadlock 3 and the new formula, 92% and 95% of all fetal weight estimations were within 10% of actual birth weight, respectively. Measurement of VAT and SF thickness in prediction of fetal weight could reduce a weight estimation error. Impact statement What is already known on this subject? An accurate prediction of fetal weight during gestation provides useful information for assessing the fetal and newborn health status. As the detection of growth abnormalities is vital, there is a need for a reliable method of assessing birth weight during labour. Unfortunately, although different methods are available, a simple, quick and reliable method of assessing birth weight is still in debate. Fetal visceral adipose (VAT) tissue measurement is a new method which could be used for the correct estimation of fetal weight. Like adults, the VAT and subcutaneous fat tissue (SF) thickness could be correlated with the weight and body-mass index. What do the results of this study add? It was found that SF and VAT are important factors in the prediction of birth weight, like the abdominal circumference (AC). What are the implications of these findings for clinical practice and/or further research? The measurement of VAT and SF thickness in prediction of fetal weight could reduce a weight estimation error.

摘要

本研究的目的是评估一种计算估计胎儿体重(EFW)的新公式的准确性,并评估胎儿内脏脂肪组织(VAT)和腹部皮下脂肪(SF)厚度对出生体重预测的价值。在这项前瞻性研究中,通过超声检查对37至41孕周的低风险孕妇进行胎儿生物测量、EFW、胎儿VAT和SF厚度测量。进行线性回归分析以研究出生体重与产科测量之间的关系。结果发现,预测出生体重的最重要因素是腹围(AC)、SF和VAT。EFW的新公式为 根据Hadlock 3公式和新公式,分别有92%和95%的胎儿体重估计值在实际出生体重的10%以内。测量VAT和SF厚度以预测胎儿体重可减少体重估计误差。影响声明 关于这个主题已经知道了什么?孕期准确预测胎儿体重可为评估胎儿和新生儿健康状况提供有用信息。由于检测生长异常至关重要,因此需要一种在分娩期间评估出生体重的可靠方法。不幸的是,尽管有不同的方法可用,但一种简单、快速且可靠的评估出生体重的方法仍存在争议。胎儿内脏脂肪(VAT)组织测量是一种可用于正确估计胎儿体重的新方法。与成年人一样,VAT和皮下脂肪组织(SF)厚度可能与体重和体重指数相关。本研究的结果增加了什么?结果发现,SF和VAT是预测出生体重的重要因素,与腹围(AC)一样。这些发现对临床实践和/或进一步研究有何影响?测量VAT和SF厚度以预测胎儿体重可减少体重估计误差。

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