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术后小儿泌尿科患者阿片类药物的处方模式、储存、处理和处置。

Opioid-prescribing patterns, storage, handling, and disposal in postoperative pediatric urology patients.

机构信息

The University of North Carolina at Chapel Hill, Department of Urology, USA.

The University of North Carolina at Chapel Hill, Department of Anesthesiology, 101 Manning Drive, Chapel Hill, NC, 27514, USA.

出版信息

J Pediatr Urol. 2019 May;15(3):260.e1-260.e7. doi: 10.1016/j.jpurol.2019.02.009. Epub 2019 Feb 23.

Abstract

BACKGROUND

Emerging research on surgeons and the opioid epidemic have focused on the adult population. Consequently, little is known regarding opioid-prescribing practices in the pediatric population. The goal of this study is to examine postoperative opioid-prescribing and consumption patterns, as well as storage and disposal trends for specific pediatric urologic procedures.

STUDY DESIGN

Patients undergoing surgery associated with specified Current Procedural Terminology codes were retrospectively identified, and details regarding opioid medications were obtained through our pharmacy database. Patients' guardians were contacted two weeks postoperatively to determine opioid usage. Opioids were prescribed at a standard dosing of 0.1 mg/kg per dose or the equivalent.

RESULTS

Of the 171 identified patients, 117 patients were successfully contacted, with 67 (39%) completing telephone surveys. The 3 most common pediatric urology procedures were inguinal hernia repair (N = 39), circumcision (N = 27), and cystoscopy (N = 16). Across all procedures, there was an average excess of 9.8 doses prescribed, corresponding to an overprescription rate of 64%. Of the patients prescribed opioids, 41 (62%) had leftover opioid medication two weeks postoperatively. Thirty-two of 41 (78%) patients did not dispose of their leftover medication. Only 13 patients received perioperative counseling on appropriate storage and disposal of opiates.

DISCUSSION

Prescribing practices for an array of pediatric urologic procedures are non-standardized and often generously excessive. We show universal overprescribing for all our reviewed urologic procedures. Sixty-two percent of pediatric urology patients did not use their entire prescribed opiate, leaving a significant pool of medicine within the pediatric family home. Given the low incidence of perioperative education, unsurprisingly a majority of our patients improperly handled and disposed off excess opioid medication.

CONCLUSION

There is general overprescription of postoperative opioids and poor perioperative opioid education in the pediatric urology population.

摘要

背景

有关外科医生和阿片类药物泛滥的新兴研究集中在成年人群体。因此,对于儿科人群的阿片类药物处方实践知之甚少。本研究的目的是检查特定儿科泌尿科手术的术后阿片类药物处方和使用模式,以及储存和处置趋势。

研究设计

通过我们的药房数据库,回顾性确定接受特定当前程序术语 (Current Procedural Terminology, CPT) 代码手术的患者,并获取有关阿片类药物的详细信息。术后两周联系患者监护人以确定阿片类药物的使用情况。阿片类药物的处方剂量为 0.1mg/kg/剂或等效剂量。

结果

在 171 名确定的患者中,成功联系了 117 名患者,其中 67 名(39%)完成了电话调查。最常见的三种儿科泌尿科手术是腹股沟疝修补术 (N=39)、包皮环切术 (N=27) 和膀胱镜检查 (N=16)。所有手术中,平均处方剂量超过 9.8 剂,对应于 64%的过度处方率。在接受阿片类药物处方的患者中,41 名(62%)在术后两周仍有剩余的阿片类药物。41 名患者中的 32 名 (78%) 没有处理剩余药物。只有 13 名患者接受了围手术期关于阿片类药物适当储存和处理的咨询。

讨论

一系列儿科泌尿科手术的处方实践是非标准化的,且往往过于慷慨。我们展示了所有审查过的泌尿科手术的普遍过度处方。62%的儿科泌尿科患者没有使用他们全部规定的阿片类药物,这使得儿科家庭中存在大量剩余药物。考虑到围手术期教育的发生率低,我们的患者中大多数人处理和处置剩余阿片类药物不当,这并不奇怪。

结论

儿科泌尿科人群中普遍存在术后阿片类药物过度处方和围手术期阿片类药物教育不足的情况。

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