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Direct oral anticoagulants in extremely obese patients: OK to use?

作者信息

Moll Stephan, Crona Daniel J, Martin Karlyn

机构信息

Division of Hematology-Oncology Department of Medicine University of North Carolina School of Medicine Chapel Hill North Carolina.

Division of Pharmacotherapy University of North Carolina Eshelman School of Pharmacy Chapel Hill North Carolina.

出版信息

Res Pract Thromb Haemost. 2018 Dec 24;3(2):152-155. doi: 10.1002/rth2.12178. eCollection 2019 Apr.

Abstract
摘要

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本文引用的文献

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Peak plasma concentration of direct oral anticoagulants in obese patients weighing over 120 kilograms: A retrospective study.
Res Pract Thromb Haemost. 2018 Aug 29;2(4):684-688. doi: 10.1002/rth2.12146. eCollection 2018 Oct.
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Monitoring of Apixaban in a Super Obese Patient.
Am J Med. 2019 Jan;132(1):e15-e16. doi: 10.1016/j.amjmed.2018.08.021. Epub 2018 Sep 7.
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The impact of body weight on rivaroxaban pharmacokinetics.
Res Pract Thromb Haemost. 2017 Oct 9;1(2):180-187. doi: 10.1002/rth2.12039. eCollection 2017 Oct.
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Integrated Population Pharmacokinetic Analysis of Rivaroxaban Across Multiple Patient Populations.
CPT Pharmacometrics Syst Pharmacol. 2018 May;7(5):309-320. doi: 10.1002/psp4.12288. Epub 2018 Apr 16.
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Impact of BMI on clinical outcomes of NOAC therapy in daily care - Results of the prospective Dresden NOAC Registry (NCT01588119).
Int J Cardiol. 2018 Jul 1;262:85-91. doi: 10.1016/j.ijcard.2018.03.060. Epub 2018 Mar 14.
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Laboratory Assessment of the Anticoagulant Activity of Direct Oral Anticoagulants: A Systematic Review.
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