Sah Ramesh Prasad, Talukder Md Hasanuzzaman, Rahman A K M Anisur, Alam Mohammad Zahangir, Ward Michael P
Department of Parasitology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh; Agriculture Research Station, Pakhribas, Dhankuta, Nepal Agricultural Research Council, Nepal.
Department of Parasitology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Vet Parasitol Reg Stud Reports. 2018 Jan;11:1-5. doi: 10.1016/j.vprsr.2017.10.008. Epub 2017 Nov 2.
To estimate the seroprevalence of toxoplasmosis and risk factors for seropositivity in sheep, goats and cattle in Dhaka, Mymensingh, Sirajganj and Chittagong districts in Bangladesh, 1104 sera samples (552 sheep, 300 goats and 252 cattle) were randomly selected and tested by an indirect enzyme linked immunosorbent assay (iELISA). The overall seroprevalence was 12.2% (135/1104), and was significantly (P=0.008) higher in goats (16.0%) than cattle (8.3%). The odds of seropositivity was 2.09 times (95% confidence interval [CI]: 1.23-3.67) higher in goats than cattle. In sheep, herd type, district and pregnancy status were significant risk factors. The odds of seropositivity was 2.1 (95% CI: 1.00-4.84), 7.29 (95% CI: 12.71-423.41) and 10.88 (95% CI: 5.42-23.41 times higher in sheep-only flocks, in Mymensingh district and in pregnant sheep than in mixed flocks, Chittagong district and non-pregnant sheep, respectively. In cattle, breeds and district were significant risk factors. The odds of seropositivity was 5.79 (95% CI: 1.13-24.62) and 4.29 (95% CI: 1.38-16.34) times higher in Holstein Friesian cross cattle and in Mymensingh district than in indigenous cattle and Chittagong district, respectively. This study indicates that exposure of sheep, goats and cattle to oocysts of T. gondii is widespread, suggesting that the consumption of raw and undercooked meat of these animals might be a source of human toxoplasmosis. Risk factor information can be used to design control programs to reduce exposure.
为估算孟加拉国达卡、迈门辛、锡拉杰甘杰和吉大港地区绵羊、山羊和牛的弓形虫病血清阳性率及血清阳性的风险因素，随机选取了1104份血清样本（552份绵羊样本、300份山羊样本和252份牛样本），并采用间接酶联免疫吸附测定法（iELISA）进行检测。总体血清阳性率为12.2%（135/1104），山羊的血清阳性率（16.0%）显著高于牛（8.3%）（P = 0.008）。山羊血清阳性的几率比牛高2.09倍（95%置信区间[CI]：1.23 - 3.67）。在绵羊中，畜群类型、地区和妊娠状态是显著的风险因素。仅养绵羊的畜群、在迈门辛地区以及怀孕绵羊的血清阳性几率分别比混合畜群、吉大港地区和未怀孕绵羊高2.1倍（95% CI：1.00 - 4.84）、7.29倍（95% CI：12.71 - 423.41）和10.88倍（95% CI：5.42 - 23.41）。在牛中，品种和地区是显著的风险因素。荷斯坦弗里生杂交牛和在迈门辛地区的血清阳性几率分别比本地牛和吉大港地区高5.79倍（95% CI：1.13 - 24.62）和4.29倍（95% CI：1.38 - 16.34）。本研究表明，绵羊、山羊和牛接触刚地弓形虫卵囊的情况很普遍，这表明食用这些动物的生肉和未煮熟的肉可能是人类弓形虫病的一个来源。风险因素信息可用于设计控制方案以减少接触。
