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动物和人类中的弓形虫病:孟加拉国一种被忽视的人畜共患病。

Toxoplasmosis in animals and humans: a neglected zoonotic disease in Bangladesh.

作者信息

Hasan Md Farhan, Harun Anas Bin, Hossain Delower, Bristi Sabiha Zarin Tasnim, Uddin A H M Musleh, Karim Md Robiul

机构信息

Department of Medicine, Faculty of Veterinary Medicine and Animal Science, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, 1706 Bangladesh.

Department of Medicine and Public Health, Faculty of Animal Science and Veterinary Medicine, Sher-e-Bangla Agricultural University, Dhaka, 1207 Bangladesh.

出版信息

J Parasit Dis. 2024 Jun;48(2):189-200. doi: 10.1007/s12639-024-01664-4. Epub 2024 Apr 6.

Abstract

Toxoplasmosis, caused by , is a zoonotic disease that affects a wide range of warm-blooded animals, including humans. The parasite undergoes both sexual and asexual reproduction in intermediate hosts (humans and animals) and definitive hosts (cats). Transmission in humans occurs through consuming oocyst-contaminated water, fruits, vegetables, and raw or undercooked meats. In Bangladesh, several factors contribute to an increased risk of contracting toxoplasmosis. The parasite is reported to cause diseases among livestock such as goats and sheep in this country, and it has also been associated with some human illnesses. Toxoplasmosis prevalence varies significantly worldwide, with developing countries like Bangladesh experiencing higher rates. Diagnostic methods include both conventional non-DNA-based tests and molecular detection techniques, while treatment options involve using antiparasitic drugs like sulfadiazine and pyrimethamine. To control toxoplasmosis, essential steps include improving sanitation, promoting safe food handling, and educating the public about risks related to cat ownership and undercooked meat consumption. Implementing prenatal screening and treatment is also important. With the growing popularity of pet ownership in urban areas, it becomes essential to emphasize the veterinary and public health significance of toxoplasmosis in Bangladesh. This article comprehensively reviews various aspects of toxoplasmosis, with a specific focus on the situation in Bangladesh.

摘要

由弓形虫引起的弓形虫病是一种人畜共患病,可影响包括人类在内的多种温血动物。该寄生虫在中间宿主(人类和动物)和终末宿主(猫)中进行有性和无性繁殖。人类通过饮用受卵囊污染的水、食用受污染的水果、蔬菜以及生的或未煮熟的肉类而感染。在孟加拉国,有几个因素导致感染弓形虫病的风险增加。据报道,该寄生虫在该国导致山羊和绵羊等家畜患病,并且也与一些人类疾病有关。弓形虫病的患病率在全球范围内差异很大,像孟加拉国这样的发展中国家患病率较高。诊断方法包括传统的非基于DNA的检测和分子检测技术,而治疗选择包括使用磺胺嘧啶和乙胺嘧啶等抗寄生虫药物。为了控制弓形虫病,关键步骤包括改善卫生条件、促进安全的食品处理以及教育公众有关养猫和食用未煮熟肉类的风险。实施产前筛查和治疗也很重要。随着城市地区养宠物的日益普及,强调弓形虫病在孟加拉国的兽医和公共卫生意义变得至关重要。本文全面回顾了弓形虫病的各个方面,特别关注孟加拉国的情况。

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