Hayashi Ken, Sato Tatsuhiko, Manabe Shin-Ichi, Hirata Akira
Hayashi Eye Hospital, Fukuoka, Japan.
Hayashi Eye Hospital, Fukuoka, Japan.
Ophthalmol Retina. 2019 Mar;3(3):237-243. doi: 10.1016/j.oret.2018.10.017. Epub 2018 Nov 9.
To compare the difference in the progression of posterior vitreous detachment (PVD) between men and women in relation to age.
Observational cross-sectional study.
One hundred eyes of 100 male patients and 100 eyes of 100 female patients in 4 age groups: 40 to 49 years of age, 50 to 59 years of age, 60 to 69 years of age, and 70 years of age or older.
Using swept-source (SS) OCT, PVD was classified into 5 stages: 0, no PVD; 1, paramacular PVD; 2, perifoveal PVD; 3, vitreofoveal separation; and 4, complete PVD. The PVD stage distribution was compared between men and women in the 4 age groups and among the age groups.
Stage of PVD determined using SS OCT.
In both male and female eyes, the stage of PVD progressed significantly in association with the age group (P < 0.0001). The distribution of the PVD stage did not differ significantly between men and women in the 40- to 49- and the 50- to 59-year age groups. The distribution of the PVD stage was significantly more progressed in women than in men, however, in those 60 to 69 years of age and those 70 years of age and older (P ≤ 0.0292). At 40 to 49 years of age, no PVD (stage 0) and paramacular PVD (stage 1) were detected in 92 (92.0%) female eyes and 93 (93.0%) male eyes. At 70 years of age or older, vitreofoveal separation (stage 3) and complete PVD (stage 4) were detected in 93 (93.0%) female eyes and 78 (78.0%) male eyes.
Posterior vitreous detachment significantly progresses with age in both genders, specifically between 40 years of age and 70 years of age or older. Posterior vitreous detachment progression occurs significantly faster in female eyes than in male eyes at 60 years of age or older, suggesting that the macular pathologic features associated with PVD occur at a younger age in women.
比较男性和女性在年龄相关的玻璃体后脱离（PVD）进展方面的差异。
观察性横断面研究。
4个年龄组的100例男性患者的100只眼和100例女性患者的100只眼，年龄组分别为40至49岁、50至59岁、60至69岁以及70岁及以上。
使用扫频源（SS）光学相干断层扫描（OCT），将PVD分为5个阶段：0期，无PVD；1期，黄斑旁PVD；2期，中心凹周围PVD；3期，玻璃体-中心凹分离；4期，完全PVD。比较4个年龄组中男性和女性之间以及各年龄组之间的PVD阶段分布。
使用SS OCT确定的PVD阶段。
在男性和女性眼中，PVD阶段均随年龄组显著进展（P < 0.0001）。在40至49岁和50至59岁年龄组中，男性和女性的PVD阶段分布无显著差异。然而，在60至69岁以及70岁及以上的人群中，女性的PVD阶段分布进展显著快于男性（P≤0.0292）。在40至49岁时，92只（92.0%）女性眼中和93只（93.0%）男性眼中未检测到PVD（0期）和黄斑旁PVD（1期）。在70岁及以上时，93只（93.0%）女性眼中和78只（78.0%）男性眼中检测到玻璃体-中心凹分离（3期）和完全PVD（4期）。
玻璃体后脱离在两性中均随年龄显著进展，特别是在40岁至70岁及以上之间。在60岁及以上时，女性眼中玻璃体后脱离的进展明显快于男性，这表明与PVD相关的黄斑病理特征在女性中出现的年龄更小。
