Sia Tonnii, Podin Yuwana, Chuah Teik-Beng, Wong Jin-Shyan
Medical Department, Hospital Bintulu, Jalan Nyabau, Bintulu, Sarawak, Malaysia.
Institute of Health and Community Medicine, Universiti Malaysia Sarawak, Sarawak, Malaysia.
Eur Heart J Case Rep. 2018 May 2;2(2):yty055. doi: 10.1093/ehjcr/yty055. eCollection 2018 Jun.
As a causal organism in infective endocarditis, is rare. is intrinsically resistant to aminoglycosides but a gentamicin-susceptible strain was discovered in Sarawak, Malaysian Borneo in 2010. We report the first occurrence of infective endocarditis due to the gentamicin-susceptible strain of .
A 29-year-old man presented with pneumonia and melioidosis septicaemia. His condition was complicated with infective endocarditis and septic emboli to the brain. Despite difficulties in reaching a diagnosis, the patient was successfully treated using intravenous gentamicin and ceftazidime and was discharged well.
The role of gentamicin in the treatment of the gentamicin-susceptible strain of remains unclear.
作为感染性心内膜炎的致病微生物,[具体名称未给出]很罕见。[该微生物]对氨基糖苷类药物具有内在抗性,但2010年在马来西亚婆罗洲的砂拉越发现了一株对庆大霉素敏感的菌株。我们报告了首例由对庆大霉素敏感的[该微生物]菌株引起的感染性心内膜炎。
一名29岁男性出现肺炎和类鼻疽败血症。他的病情并发感染性心内膜炎和脑部脓毒性栓子。尽管诊断困难,但患者通过静脉注射庆大霉素和头孢他啶成功治愈并康复出院。
庆大霉素在治疗对庆大霉素敏感的[该微生物]菌株中的作用仍不清楚。