氨基糖苷类药物在实验中对铜绿假单胞菌的体内作用。
In vivo effect of aminoglycoside on Pseudomonas aeruginosa in experiment.
作者信息
Uxová M, Vrbová E, Výmola F
出版信息
Czech Med. 1986;9(4):206-9.
PMID:3102186
Abstract
In artificial pseudomonas infections undertaken on white mice the effectiveness of the aminoglycosides (gentamicin, tobramycin, netilmicin, amikacin) was compared. The most effective drugs on highly susceptible Ps. aeruginosa were amikacin and netilmicin. Moreover amikacin is probably capable of inhibiting pseudomonas toxin production. Therefore this preparation should be left in reserve for the treatment of serious pseudomonas processes.
摘要
在对白鼠进行的人工假单胞菌感染实验中，比较了氨基糖苷类药物（庆大霉素、妥布霉素、奈替米星、阿米卡星）的有效性。对高度敏感的铜绿假单胞菌最有效的药物是阿米卡星和奈替米星。此外，阿米卡星可能能够抑制假单胞菌毒素的产生。因此，这种制剂应留作治疗严重假单胞菌感染的备用药物。
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