Sachdeva Julie, Bansal Ramandeep, Takkar Aastha, Singh Rajveer
Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India.
Department of Gynecology and Obstetrics, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India.
BMJ Case Rep. 2019 Apr 24;12(4):e227435. doi: 10.1136/bcr-2018-227435.
Paraneoplastic neuromyelitis optica spectrum disorder (NMOSD) is a rare clinical entity with less than 40 cases described in literature until today. Paraneoplastic NMOSD in association with adenocarcinoma of ovary has not been described yet. We present a case of paraneoplastic NMOSD in association with carcinoma ovary which improved following appropriate immunomodulation with pulse intravenous methylprednisolone and azathioprine.
副肿瘤性视神经脊髓炎谱系障碍(NMOSD)是一种罕见的临床病症,迄今为止文献中报道的病例不足40例。副肿瘤性NMOSD合并卵巢腺癌的情况尚未见报道。我们报告一例副肿瘤性NMOSD合并卵巢癌的病例,该病例在接受静脉注射甲泼尼龙冲击治疗和硫唑嘌呤进行适当免疫调节后病情有所改善。