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阿哌沙班在疗效、有效性及单臂研究中的应用探索:2019年5月《急诊医学年鉴》期刊俱乐部

Adventures With Andexanet Alfa in Efficacy, Effectiveness, and One-Armed Studies: May 2019 Annals of Emergency Medicine Journal Club.

作者信息

Radecki Ryan P, Spiegel Rory J

机构信息

Northwest Permanente, Portland, OR; The University of Texas Health Science Center at Houston, Houston, TX.

University of Maryland, Baltimore, MD.

出版信息

Ann Emerg Med. 2019 May;73(5):545-547. doi: 10.1016/j.annemergmed.2019.03.015.

DOI:10.1016/j.annemergmed.2019.03.015
PMID:31029291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7469227/
Abstract

You are reading the 70th installment of Annals of Emergency Medicine Journal Club. As the Journal Club enters its second decade of publication, the format has been revised and will focus on a monthly succinct review of high-impact articles from this journal and other premier medical journals relevant to emergency medicine. The reviews are followed by questions demonstrating principles by which readers—be they clinicians, academics, residents, or medical students—may critically appraise the literature. We are interested in receiving feedback about this feature. Please e-mail journalclub@acep.org with your comments.

摘要

您正在阅读《急诊医学杂志俱乐部》的第70期。随着该杂志俱乐部进入出版的第二个十年,其形式已经修订,将专注于每月对本杂志以及其他与急诊医学相关的顶级医学杂志上的高影响力文章进行简要回顾。这些回顾之后会有一些问题,展示读者(无论是临床医生、学者、住院医师还是医学生)用以批判性评价文献的原则。我们希望收到关于此板块的反馈。请将您的意见发送至journalclub@acep.org。

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Adventures With Andexanet Alfa in Efficacy, Effectiveness, and One-Armed Studies: May 2019 Annals of Emergency Medicine Journal Club.阿哌沙班在疗效、有效性及单臂研究中的应用探索:2019年5月《急诊医学年鉴》期刊俱乐部
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引用本文的文献

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Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel.抗凝剂在急诊科的逆转策略:多学科专家小组的建议。
Ann Emerg Med. 2020 Oct;76(4):470-485. doi: 10.1016/j.annemergmed.2019.09.001. Epub 2019 Nov 13.
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Andexanet Response.安多凝血素反应。
Ann Emerg Med. 2019 Nov;74(5):724-725. doi: 10.1016/j.annemergmed.2019.05.033.

本文引用的文献

1
Andexxa--an antidote for apixaban and rivaroxaban.安多昔(Andexxa)——一种用于阿哌沙班和利伐沙班的解毒剂。
Med Lett Drugs Ther. 2018 Jun 18;60(1549):99-101.
2
Most medical practices are not parachutes: a citation analysis of practices felt by biomedical authors to be analogous to parachutes.大多数医学实践并非降落伞:对生物医学作者认为类似于降落伞的实践进行的引文分析。
CMAJ Open. 2018 Jan 15;6(1):E31-E38. doi: 10.9778/cmajo.20170088.
3
Idarucizumab for Dabigatran Reversal - Full Cohort Analysis.达比加群酯逆转剂依达鲁珠单抗:全队列分析。
N Engl J Med. 2017 Aug 3;377(5):431-441. doi: 10.1056/NEJMoa1707278. Epub 2017 Jul 11.
4
Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: A Statement for Healthcare Professionals from the Neurocritical Care Society and Society of Critical Care Medicine.颅内出血中抗栓药物逆转指南:神经重症监护学会和危重症医学会给医疗保健专业人员的声明
Neurocrit Care. 2016 Feb;24(1):6-46. doi: 10.1007/s12028-015-0222-x.
5
Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity.依达赛珠单抗用于逆转 Xa 因子抑制剂的活性。
N Engl J Med. 2015 Dec 17;373(25):2413-24. doi: 10.1056/NEJMoa1510991. Epub 2015 Nov 11.
6
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.《世界医学协会赫尔辛基宣言:涉及人类受试者的医学研究伦理原则》
JAMA. 2013 Nov 27;310(20):2191-4. doi: 10.1001/jama.2013.281053.
7
Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials.使用降落伞预防与重力挑战相关的死亡和重大创伤:随机对照试验的系统评价
BMJ. 2003 Dec 20;327(7429):1459-61. doi: 10.1136/bmj.327.7429.1459.