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[通过静脉内和皮下注射曼氏血吸虫尾蚴感染实验动物的比较效率]

[Comparative efficiency of infecting laboratory animals via intravenous and subcutaneous administration of Schistosoma mansoni cercaria].

作者信息

Zelia O P, Kovalenko F P

出版信息

Parazitologiia. 1986 Nov-Dec;20(6):461-5.

PMID:3103045
Abstract

Comparative study on effectiveness of intravenous and subcutaneous methods of infection of animals has shown that infection rate of helminths after the injection of equal dozes of cercariae under skin, into portal and femoral veins of golden hamsters does not differ significantly (42.6 +/- 4.2, 37.8 +/- 5.8 and 26.0 +/- 6.6 schistosomes, respectively). When using the above methods for cotton rats the infection rate was lower than that in golden hamsters. The most insignificant infection rate of parasites was recorded in both species after the injection of cercariae into the femoral vein. Results of the infection of golden hamsters with different dozes of cercariae have shown that with the increase of dozes of infectious material the infection rate of helminths rises during the experimental intestinal schistosomiasis only to a definite level, which is attained by the injection of cercariae into the portal vein in dozes lower than those used for subcutaneous infection.

摘要

对动物进行静脉注射和皮下注射感染方法的有效性比较研究表明,在给金黄仓鼠的皮肤下、门静脉和股静脉注射等量尾蚴后,蠕虫的感染率没有显著差异(分别为42.6±4.2、37.8±5.8和26.0±6.6条血吸虫)。当对棉鼠使用上述方法时,感染率低于金黄仓鼠。在将尾蚴注射到股静脉后,两种动物的寄生虫感染率最低。用不同剂量尾蚴感染金黄仓鼠的结果表明,在实验性肠道血吸虫病中,随着感染物质剂量的增加,蠕虫的感染率仅上升到一定水平,通过向门静脉注射低于皮下感染所用剂量的尾蚴即可达到这一水平。

相似文献

1
[Comparative efficiency of infecting laboratory animals via intravenous and subcutaneous administration of Schistosoma mansoni cercaria].[通过静脉内和皮下注射曼氏血吸虫尾蚴感染实验动物的比较效率]
Parazitologiia. 1986 Nov-Dec;20(6):461-5.
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[Laboratory animal infection in modeling intestinal schistosomiasis].
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[Wild rodents as experimental models of schistosomiasis mansoni: Akodon arviculoides (Rodentia: Cricetidae)].
Rev Inst Med Trop Sao Paulo. 1991 Jul-Aug;33(4):257-61.
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Study of the morphological characteristics of Schistosoma mansoni in mice, squirrels, and hamsters.曼氏血吸虫在小鼠、松鼠和仓鼠体内的形态学特征研究。
Southeast Asian J Trop Med Public Health. 2006 Jan;37(1):33-9.
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Infection of mice with cercariae and schistosomula of Schistosoma mansoni by intravenous and subcutaneous routes.通过静脉内和皮下途径用曼氏血吸虫尾蚴和童虫感染小鼠。
Rev Inst Med Trop Sao Paulo. 1974 May-Jun;16(3):132-4.
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[Features of the isolation of Schistosoma mansoni eggs in experimentally infested golden and Djungarian hamsters].
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Worm development in hamsters infected with unisex and cross-mated Schistosoma mansoni and Schistosoma haematobium.感染单性及交叉交配的曼氏血吸虫和埃及血吸虫的仓鼠体内蠕虫的发育情况。
J Parasitol. 1995 Feb;81(1):8-11.
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In vivo microscopy of schistosomiasis. IV. The dynamics of the host-parasite responses to Schistosoma mansoni in the hypodermal tissues as observed in transparent chambers in two susceptible hosts during primary and challenge infections.
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Schistosoma mansoni nephropathy in Syrian golden hamsters: effect of dose and duration of infection.叙利亚金仓鼠的曼氏血吸虫肾病:感染剂量和持续时间的影响
Nephron. 1991;59(1):121-30. doi: 10.1159/000186531.
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Mating interactions between Schistosoma haematobium and S. mansoni.埃及血吸虫与曼氏血吸虫之间的交配相互作用。
J Helminthol. 1999 Dec;73(4):351-6.

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