Semenkovich Tara R, Frye C Corbin, Harrison M Shea, Subramanian Melanie, Kozower Benjamin D, Meyers Bryan F, Puri Varun
Division of Cardiothoracic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA.
J Thorac Dis. 2019 Mar;11(Suppl 4):S555-S561. doi: 10.21037/jtd.2019.01.18.
Interventional studies are designed specifically to test the impact of a treatment or management strategy on an outcome of interest. In this article, we will highlight two viewpoints regarding the role of small or single-institution prospective interventional studies within the field of thoracic surgery: first, that these studies are beneficial and can positively impact the field, and second, that these studies can have such significant limitations that they may have no meaningful impact. We will also review elements that can make for successful design and execution of small prospective interventional studies.
干预性研究旨在专门测试一种治疗或管理策略对感兴趣的结果的影响。在本文中，我们将重点介绍关于胸外科领域中小规模或单机构前瞻性干预性研究作用的两种观点：第一，这些研究是有益的，并且可以对该领域产生积极影响；第二，这些研究可能存在重大局限性，以至于可能没有有意义的影响。我们还将回顾有助于成功设计和实施小规模前瞻性干预性研究的要素。
