一名患有巨细胞病毒性视网膜炎和自体造血细胞移植后免疫重建性葡萄膜炎的淋巴瘤患者：病例报告及文献复习
A lymphoma patient with Cytomegalovirus retinitis and post-autologous hematopoietic cell transplantation immune reconstitution uveitis: A case report and review of the literature.
作者信息
Fuller Risa, Strauss Danielle, Steinberg Amir, Rana Meenakshi, Keyzner Alla, Dunn Dallas, Jacobs Samantha E
机构信息
Department of Medicine, Division of Infectious Disease, Icahn School of Medicine at Mount Sinai, New York, New York.
OMNI Eye Surgery, New York, New York.
出版信息
Transpl Infect Dis. 2019 Aug;21(4):e13099. doi: 10.1111/tid.13099. Epub 2019 May 11.
Cytomegalovirus (CMV) retinitis in hematologic malignancies in the absence of hematopoietic cell transplant (HCT) is uncommon. We report a case of a 54-year-old woman with peripheral T-cell lymphoma who develops CMV retinitis and subsequently undergoes an autologous HCT, with eventual development of immune reconstitution uveitis. We further reviewed the PubMed literature on CMV retinitis in patients with lymphoma. We describe that CMV retinitis in patients with lymphoma has variable clinical presentations, may occur at any time during the course of the disease and chemotherapy, and is associated with significant morbidity.
在无造血细胞移植（HCT）的血液系统恶性肿瘤中，巨细胞病毒（CMV）视网膜炎并不常见。我们报告一例54岁患有外周T细胞淋巴瘤的女性，其发生了CMV视网膜炎，随后接受了自体HCT，最终发展为免疫重建性葡萄膜炎。我们进一步回顾了PubMed上关于淋巴瘤患者CMV视网膜炎的文献。我们描述了淋巴瘤患者的CMV视网膜炎有多种临床表现，可在疾病和化疗过程中的任何时间发生，且与显著的发病率相关。
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