Orces Carlos
Laredo Medical Center.
Nutr Hosp. 2019 Jul 1;36(3):571-577. doi: 10.20960/nh.2507.
Background: older adults are at increased risk of vitamin D deficiency as a result of limited sun exposure and inadequate vitamin D intake. Despite this evidence, there are scarce data regarding the concentration of 25(OH)D and its metabolites among older adults with physical disability. Methods: the National Health and Nutrition Examination Survey 2007-2014 data were collected to compare 25(OH)D3, 25(H)D2, and total 25(OH)D concentrations among adults aged 60 years and older with and without physical disability. Moreover, general linear models adjusted for potential confounders were used to examine the independent effect of vitamin D intake, physical activity status and body mass index (BMI) categories on 25(OH)D concentrations by disability status. Results: of 6,250 older adults, 17.9% were defined as physically disabled. 25(OH)D concentrations were 71.3 and 78.2 nmol/l in subjects with and without disability, respectively. However, after adjustment for potential confounders, similar 25(OH)D concentrations were seen between disabled subjects and their non-disabled counterparts (75.6 vs 77.5 nmol/l; p = 1.17). In contrast, older adults with disability had significantly increased 25(OH)D2 concentrations (8.3 vs 6.1 nmol/l; p < 0.05). Notably, older adults with a daily vitamin D intake of ≥ 15 mcg achieved sufficient 25(OH)D concentrations, regardless of their disability status. Conclusion: 25(OH)D concentrations did not significantly differ among older adults by disability status. This finding was attributed to increased 25(OH)D2 concentrations among those with physical disability. Thus, adequate vitamin D intake is an effective strategy to maintain sufficient 25(OH)D concentrations, particularly among disabled older adults.
由于日照有限和维生素D摄入不足，老年人维生素D缺乏风险增加。尽管有此证据，但关于身体残疾老年人中25(OH)D及其代谢物浓度的数据却很少。方法：收集2007 - 2014年美国国家健康与营养检查调查数据，以比较60岁及以上有身体残疾和无身体残疾成年人的25(OH)D3、25(OH)D2和总25(OH)D浓度。此外，采用针对潜在混杂因素进行调整的一般线性模型，按残疾状况研究维生素D摄入量、身体活动状况和体重指数（BMI）类别对25(OH)D浓度的独立影响。结果：在6250名老年人中，17.9%被定义为身体残疾。残疾和非残疾受试者的25(OH)D浓度分别为71.3和78.2 nmol/l。然而，在对潜在混杂因素进行调整后，残疾受试者与其非残疾对应者的25(OH)D浓度相似（75.6对77.5 nmol/l；p = 1.17）。相比之下，残疾老年人的25(OH)D2浓度显著升高（8.3对6.1 nmol/l；p < 0.05）。值得注意的是，每日维生素D摄入量≥15 mcg的老年人，无论其残疾状况如何，均达到了足够的25(OH)D浓度。结论：老年人的25(OH)D浓度在残疾状况方面无显著差异。这一发现归因于身体残疾者中25(OH)D2浓度升高。因此，充足的维生素D摄入是维持足够25(OH)D浓度的有效策略，尤其是在残疾老年人中。
