Passath A, Leb G, Warnkross H
Wien Med Wochenschr. 1986 Nov 30;136(21-22):550-3.
TSH measurements using sensitive TSH-IRMA method makes differentiation of euthyroidism and hyperthyroidism possible without TSH stimulation after TRH. TSH-basal values less than 0.1 mU/L proof pituitary TSH suppression (clinical overt and latent hyperthyroidism, thyroid hormone therapy etc.). TSH-basal values between 0.4 and 4.0 mU/L are found in euthyroidism. TSH-basal values greater than 4.0 mU/L indicate latent or manifest hypothyroidism. With basal TSH values between 0.1 and 0.4 mU/L (borderline values between euthyroidism and "relative pituitary hormone excess") a TRH-test ist still necessary as it is not possible to predict stimulated TSH values from basal TSH concentrations with adequate accuracy. TSH measurements using sensitive IRMA methods may be recommanded as a screening test of thyroid function.
采用敏感促甲状腺激素免疫放射分析（TSH-IRMA）法测定促甲状腺激素，无需促甲状腺激素释放激素（TRH）刺激即可区分甲状腺功能正常与甲状腺功能亢进。促甲状腺激素基础值低于0.1 mU/L证明垂体促甲状腺激素受抑制（临床显性和隐性甲状腺功能亢进、甲状腺激素治疗等）。甲状腺功能正常时促甲状腺激素基础值在0.4至4.0 mU/L之间。促甲状腺激素基础值大于4.0 mU/L表明存在隐性或显性甲状腺功能减退。当促甲状腺激素基础值在0.1至0.4 mU/L之间（甲状腺功能正常与“相对垂体激素过多”之间的临界值）时，仍需进行TRH试验，因为无法根据促甲状腺激素基础浓度准确预测刺激后的促甲状腺激素值。采用敏感免疫放射分析方法测定促甲状腺激素可作为甲状腺功能的筛查试验。
