Müller C, Kiss H, Weber H, Kaindl F
Z Kardiol. 1986 Dec;75(12):730-6.
In a prospective study 24 hour long-term ECG (LT-ECG) recordings under ambulatory conditions were performed in 126 patients with syncopes (SY) of unknown origin. LT-ECG revealed arrhythmias (AR) in 57%, whereas 43% had inconspicuous findings. One patient developed a SY during LT-ECG without any evidence for arrhythmias. In 40% of these patients AR not detected previously by other methods were discovered. In 36% AR detected by LT-ECG had to be considered as precursors of syncopes (i.e. bradycardia less than 40 b.p.m., tachycardia greater than 160 b.p.m., AV-block II/II and III, or ventricular arrhythmias Lown IV). LT-ECG increased the information about the cause of syncope in 35%, whereas in 65% LT-ECG did not produce any further information. Consequently LT-ECG led in 56% to drug therapy, in 8% to PM-implantation. During a mean follow-up of 22 months 22% of patients developed again a syncopal attack and 4% died suddenly. Despite LT-ECG recording an ECG-registration during a typical syncopal attack for the confirmation or exclusion of an arrhythmogenic genesis of the SY is achieved only by chance. Nevertheless further informations with regard to precursing AR can be obtained, which may lead to therapeutic consequences in some patients. Therefore, LT-ECG has to be recommended as an essential, non-invasive procedure in patients with SY of unknown origin.
在一项前瞻性研究中,对126例不明原因晕厥(SY)患者进行了动态条件下24小时的长期心电图(LT-ECG)记录。LT-ECG显示57%的患者存在心律失常(AR),而43%的患者结果不明显。1例患者在LT-ECG监测期间发生晕厥,但未发现任何心律失常证据。在这些患者中,40%发现了之前其他方法未检测到的AR。LT-ECG检测到的AR中有36%被认为是晕厥的先兆(即心率低于40次/分钟的心动过缓、心率高于160次/分钟的心动过速、二度或三度房室传导阻滞或Lown IV级室性心律失常)。LT-ECG使35%的患者增加了关于晕厥原因的信息,而65%的患者未获得更多信息。因此,LT-ECG导致56%的患者接受药物治疗,8%的患者接受起搏器植入。在平均22个月的随访期间,22%的患者再次发生晕厥发作,4%的患者突然死亡。尽管进行了LT-ECG记录,但在典型晕厥发作期间进行心电图记录以确认或排除SY的心律失常性起源只是偶然实现。然而,可以获得关于先兆性AR的更多信息,这可能会在一些患者中产生治疗效果。因此,对于不明原因SY患者,LT-ECG必须被推荐为一种重要的非侵入性检查方法。