乙二胺四乙酸钾（K3 EDTA）对平均血小板体积的不可预测影响。

Unpredictable effects of K3 EDTA on mean platelet volume.

作者信息

Lippi U, Schinella M, Modena N, Nicoli M

出版信息

Am J Clin Pathol. 1987 Mar;87(3):391-3. doi: 10.1093/ajcp/87.3.391.

DOI:10.1093/ajcp/87.3.391

Abstract

The changes of mean platelet volumes (MPVs) begin immediately upon exposure of the blood to K3EDTA, and differences from sample to sample are unpredictable, predominantly in the first two hours from the venipuncture. MPVs variations can range from -25 to 23.1% in respect to MPVs in untreated whole blood immediately processed. These results were obtained by a new electrooptical device (Technicon H X 1) that provides complete blood cell counting and sizing. If whole blood is collected and diluted with a reagent used by the instrument to sphere and fix red blood cells and platelets, MPVs values do not change significantly within 180 minutes from venipuncture. This approach allows one to study the true values of MPVs on Technicon H X 1.

摘要

血液一旦接触K3EDTA，平均血小板体积（MPV）随即开始变化，样本之间的差异不可预测，主要出现在静脉穿刺后的头两小时内。与立即处理的未处理全血中的MPV相比，MPV变化范围可达-25%至23.1%。这些结果是通过一种新型电光设备（Technicon H X 1）获得的，该设备可进行全血细胞计数和大小测定。如果采集全血并用该仪器用于使红细胞和血小板形成球形并固定的试剂进行稀释，静脉穿刺后180分钟内MPV值不会有显著变化。这种方法使人们能够在Technicon H X 1上研究MPV的真实值。