Department of Pediatrics, School of Medicine, University of Valencia, Hospital Clínico Universitario of Valencia, Avenida Blasco Ibáñez 15⁻17, 46010 Valencia, Spain.
Gastroenterology and Nutrition Unit, Hospital Clínico Universitario, Avenida Blasco Ibáñez 17, 46010 Valencia, Spain.
Nutrients. 2019 Apr 26;11(5):956. doi: 10.3390/nu11050956.
The aim of the study was to assess the anthropometric outcomes after gastrostomy tube (GT) placement in children with chronic diseases and the influence of primary diagnosis, age, and nutritional support. A longitudinal, multicenter, and prospective study was performed evaluating 65 children with GT feeding and chronic diseases (61.5% with neurological disease). Each child was evaluated three times (at baseline and at 6 and 12 months after GT placement) and the following data was collected: primary diagnosis, age at GT placement, anthropometry, and feeding regime. Repeated measures ANOVA were used to analyze the main effects (intra and intergroup) and the interactions effects on weight gain and linear growth at 6 and 12 months after GT placement. All patients significantly improved their body mass index (BMI)-for-age z-score ( < 0.001) and height-for-age z-score ( < 0.05) after 6 and 12-month of follow-up. BMI gain increased significantly the first 6 months, followed by a plateau, while height followed a linear trend. Children with GT placement before 18 months old experienced an accelerated growth rate during the first 6 months post-GT. This technique showed the effectiveness of GT placement improving nutritional status and growth catch up regardless of their primary diagnosis and the type of nutritional support.
研究目的在于评估患有慢性疾病的儿童在胃造口管（GT）置管后的人体测量学结果，以及原发疾病、年龄和营养支持的影响。本研究采用前瞻性、多中心、纵向研究方法，评估了 65 例接受 GT 喂养的慢性疾病儿童（61.5%患有神经疾病）。每个孩子都在基线和 GT 置管后 6 个月和 12 个月进行了 3 次评估，收集了以下数据：原发疾病、GT 置管年龄、人体测量学和喂养方式。采用重复测量方差分析来分析体重增加和线性生长在 GT 置管后 6 个月和 12 个月的主要影响（组内和组间）和相互作用影响。所有患者在 6 个月和 12 个月的随访后，体重指数（BMI）-年龄 z 评分（ < 0.001）和身高-年龄 z 评分（ < 0.05）均显著提高。BMI 在头 6 个月增长显著，之后趋于平稳，而身高则呈线性趋势。18 个月以下儿童在 GT 置管后前 6 个月的生长速度加快。该技术表明，GT 置管可以有效改善营养状况和生长追赶，无论原发疾病和营养支持类型如何。
