Díaz-Cabanas L, Belani-Raju M, González-Márquez P I, Artioli-Schellini S, Guereñu-Panero I, Galindo-Ferreiro A
Departamento de Oftalmología, Hospital Clínico Universitario, Valladolid, España.
Departamento de Oftalmología, Hospital Universitario Río Hortega, Valladolid, España.
Arch Soc Esp Oftalmol (Engl Ed). 2019 Sep;94(9):453-459. doi: 10.1016/j.oftal.2019.03.006. Epub 2019 Apr 26.
An unusual case is presented of a 29 year-old Caucasian woman with a granuloma in an old scar in the right periocular region as a first clinical sign of a systemic sarcoidosis. An excisional biopsy was performed, for which the histological diagnosis was a chronic non-necrotising granulomatous inflammation, suggestive of scar sarcoidosis. The lesion re-appeared one year after initial treatment, and was treated with intralesional depot steroids, showing adequate progression. This disease occurs more frequently in wound areas where there are foreign bodies and could be the first sign of systemic sarcoidosis.
本文报告了一例罕见病例，一名29岁的白种女性，其右眼周区域旧瘢痕处出现肉芽肿，这是系统性结节病的首个临床症状。进行了切除活检，组织学诊断为慢性非坏死性肉芽肿性炎症，提示瘢痕结节病。病变在初始治疗一年后复发，采用病灶内长效类固醇治疗，病情进展良好。这种疾病在有异物的伤口部位更常见，可能是系统性结节病的首个症状。
