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[血栓形成后综合征]

[The Postthrombotic Syndrome].

作者信息

Jeanneret-Gris Christina

机构信息

1 Angiologie Medizinische Universitätsklinik Kantonsspital Baselland, Bruderholz.

出版信息

Ther Umsch. 2018;75(8):502-505. doi: 10.1024/0040-5930/a001031.

DOI:10.1024/0040-5930/a001031
PMID:31038049
Abstract

The Postthrombotic Syndrome The postthrombotic syndrome is defined by clinical signs (objectively assessed findings) and complaints that occur after a deep vein thrombosis. The most commonly used score is the Villalta score, but the most easily applicable is the Ginsberg score (pain, swelling > 1 month). Unfortunately, the current scores are not specific in this respect and are used differently in the different studies. The natural course of deep vein thrombosis during anticoagulation and the occurrence of a postthrombotic syndrome are important predictors of the long-term outcome. Four large controlled studies examined the effect of compression stockings on the development of a postthrombotic syndrome, they are summarized and discussed in this paper. Whether compression stocking do or do not prevent a postthrombotoc syndrome is questioned. Duplex sonographic findings such as residual thrombusload and postthrombotic venous reflux are unfortunately not predictive for the development of a postthrombotic syndrome, as shown in a prospective study.

摘要

血栓形成后综合征 血栓形成后综合征由深静脉血栓形成后出现的临床体征(客观评估的结果)和症状所定义。最常用的评分是维拉塔评分,但最易于应用的是金斯伯格评分(疼痛、肿胀超过1个月)。遗憾的是,目前的评分在这方面并不特异,且在不同研究中的使用方式也有所不同。抗凝期间深静脉血栓形成的自然病程以及血栓形成后综合征的发生是长期预后的重要预测因素。四项大型对照研究考察了弹力袜对血栓形成后综合征发生的影响,本文对其进行了总结和讨论。弹力袜是否能预防血栓形成后综合征受到质疑。如一项前瞻性研究所示,双功超声检查结果如残余血栓负荷和血栓形成后的静脉反流并不能预测血栓形成后综合征的发生。

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