[Effect of exogenous gangliosides on the metabolism of inositol compounds in chick neurons in primary culture].

A mixture of exogenous gangliosides at 10(-8) M and 10(-5) M concentration added to the medium of chick neurons stimulates the metabolism of inositol compounds. Notably the incorporation of [3H] myo-inositol is increased in phosphatidylinositol and in inositol triphosphate. Gangliosides, hence, by increasing the production of second messengers might regulate the phosphorylation processes of neuronal proteins.