Actin and myosinlike structure induced in the growth cartilage by acute ischemia.

Acute ischemia was induced in the lower limb of growing dogs by injecting the femoral artery with a suspension of carborundum and ground glass in physiological saline. This resulted in the loss of the cellular pattern and the cartilaginous matrix in the growth cartilage. The production of myofibrillike material was observed only in the growth cartilage as well as in the intertrabecular spaces of metaphysis in the injected leg.