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新型头孢菌素BMY - 28142的体外活性

In vitro activity of BMY-28142, a new cephalosporin.

作者信息

Norden C W, Neiderriter K

出版信息

Chemotherapy. 1987;33(1):15-7. doi: 10.1159/000238470.

Abstract

BMY-28142 was compared in vitro with ceftazidime, cefotaxime and cefoperazone and was found to be more active against Pseudomonas aeruginosa and Staphylococcus aureus. Essentially no effect of increasing inoculum size 100-fold was seen-on MICs with BMY-28142 or ceftazidime; some effect was noted with cefotaxime and cefoperazone.

摘要

在体外将BMY - 28142与头孢他啶、头孢噻肟和头孢哌酮进行比较,发现它对铜绿假单胞菌和金黄色葡萄球菌更具活性。将接种量增大100倍,对BMY - 28142或头孢他啶的最低抑菌浓度(MIC)基本上没有影响;对头孢噻肟和头孢哌酮则有一些影响。

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