Phototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rods.
作者信息
Heck Martin, Hofmann Klaus Peter, Kraft Timothy W, Lamb Trevor D
机构信息
Institut für Medizinische Physik und Biophysik der Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, D-10117 Berlin, Germany.
Zentrum für Biophysik und Bioinformatik, Humboldt-Universität zu Berlin, D-10115 Berlin, Germany.
出版信息
Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8653-8654. doi: 10.1073/pnas.1904017116.
Abstract
摘要
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Phototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rods.视网膜视杆细胞中G蛋白转导素和效应蛋白磷酸二酯酶6阶段的光转导增益。
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Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8655-8656. doi: 10.1073/pnas.1904339116.
本文引用的文献
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Elementary response triggered by transducin in retinal rods.视杆细胞中转导蛋白引发的初步反应。
Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5144-5153. doi: 10.1073/pnas.1817781116. Epub 2019 Feb 22.
2
Implications of dimeric activation of PDE6 for rod phototransduction.PDE6 二聚体激活对视杆细胞光传导的影响。
Open Biol. 2018 Aug;8(8). doi: 10.1098/rsob.180076.
3
It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods.两个转导蛋白可激活视杆细胞中的 cGMP-磷酸二酯酶 6。
Open Biol. 2018 Aug;8(8). doi: 10.1098/rsob.180075.
4
Maximal rate and nucleotide dependence of rhodopsin-catalyzed transducin activation: initial rate analysis based on a double displacement mechanism.视紫红质催化转导蛋白激活的最大速率和核苷酸依赖性：基于双置换机制的初始速率分析。
J Biol Chem. 2001 Mar 30;276(13):10000-9. doi: 10.1074/jbc.M009475200. Epub 2000 Dec 14.
5
Millisecond activation of transducin in the cyclic nucleotide cascade of vision.视觉环核苷酸级联反应中转导素的毫秒级激活。
Nature. 1984;311(5987):659-61. doi: 10.1038/311659a0.
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