Mangalat Nisha
Nisha Mangalat, MD, is the Medical Director, Glennon Intestinal Rehabilitation and Feeding Program, Department of Pediatrics, Saint Louis University, St. Louis, Missouri.
Mo Med. 2019 Mar-Apr;116(2):129-133.
The term "intestinal failure" signifies the inability of the body to meet the digestive, absorptive and nutritive needs of the body. In children, intestinal failure is most often due to short bowel syndrome, often a result of necrotizing enterocolitis, a severe GI ischemic pathology that is generally associated with prematurity. With advances in neonatal care, more preterm infants are surviving, and subsequently we care for more children with SBS than ever before. These children require parenteral nutrition (PN) for survival. Neurodevelopmental outcomes are tied to nutrition in early years; thus these children are the most vulnerable to the sequelae of intestinal failure. As such, the development of multi-disciplinary intestinal rehabilitation programs have emerged as the state of the art in the care of children with intestinal failure.
“肠衰竭”一词指身体无法满足自身消化、吸收和营养需求的状况。在儿童中，肠衰竭最常见的原因是短肠综合征，这通常是坏死性小肠结肠炎的结果，坏死性小肠结肠炎是一种严重的胃肠道缺血性病变，一般与早产有关。随着新生儿护理技术的进步，更多的早产儿得以存活，因此我们现在照顾的短肠综合征患儿比以往任何时候都多。这些儿童需要肠外营养（PN）才能生存。神经发育结果与早年的营养状况相关；因此，这些儿童最易受到肠衰竭后遗症的影响。正因如此，多学科肠道康复项目的发展已成为治疗儿童肠衰竭的先进方法。
