Gotmare Swati Shrikant, Shah Tanmik, Periera Treville, Waghmare Mandavi S, Shetty Subraj, Sonawane Sushama, Gite Maina
Department of Oral Pathology and Microbiology, School of Dentistry, DY Patil University, Navi Mumbai, Maharashtra, India.
Department of Oral Medicine and Radiology, School of Dentistry, DY Patil University, Navi Mumbai, Maharashtra, India.
Dent Res J (Isfahan). 2019 May-Jun;16(3):160-165.
Various biochemical and histological methods are available for human age determination which are invasive and may require extraction of teeth. The present study aims to assess the accuracy of age estimation from tooth-coronal index (TCI) of known age and sex individuals and to present a noninvasive method for age estimation.
This retrospective study comprised 88 patients, which included 54 males and 34 females. An orthopantomogram of these individuals were taken, and premolars and molars in the same were evaluated. The height of the crown (coronal height [CH]) and the height of the coronal pulp cavity (coronal pulp cavity height [CPCH]) was digitally measured on the computer screen. The TCI given by Ikeda . in 1985 (TCI = [CPCH × 100]/CH.) was computed on each tooth and regressed on real age of the sample. The mean, median, range, and standard deviation of the computed index were calculated. The correlation between the actual age and the estimated age was calculated using -test. < 0.05 was considered significant.
Results revealed that there is a significant correlation between the TCI with age. Increase in TCI observed with age; however, it showed no significant sex difference.
TCI is a precise, noninvasive and easily used reliable biomarker for age estimation and is applicable to both living and dead individuals.
有多种生化和组织学方法可用于确定人类年龄，这些方法具有侵入性，可能需要拔牙。本研究旨在评估根据已知年龄和性别的个体的牙冠指数（TCI）进行年龄估计的准确性，并提出一种非侵入性的年龄估计方法。
这项回顾性研究包括88名患者，其中男性54名，女性34名。拍摄了这些个体的全景曲面断层片，并对其中的前磨牙和磨牙进行了评估。在电脑屏幕上对牙冠高度（冠高[CH]）和冠髓腔高度（冠髓腔高度[CPCH]）进行数字测量。计算了池田于1985年给出的TCI（TCI = [CPCH × 100]/CH），并将其在每颗牙齿上进行计算，并与样本的实际年龄进行回归分析。计算了计算指数的均值、中位数、范围和标准差。使用检验计算实际年龄与估计年龄之间的相关性。P < 0.05被认为具有显著性。
结果显示，TCI与年龄之间存在显著相关性。随着年龄的增长，TCI升高；然而，它没有显示出显著的性别差异。
TCI是一种精确、非侵入性且易于使用的可靠年龄估计生物标志物，适用于活体和尸体个体。
