Lebovitz R M, Johnson L, Samson W K
J Appl Physiol (1985). 1987 Jan;62(1):245-52. doi: 10.1152/jappl.1987.62.1.245.
The effects on testicular function of pulse-modulated microwave radiation (PM MWR, 1.3 GHz) and of conventional heating were studied in the rat. Anesthetized adult males (Sprague-Dawley, 400-500 g) were treated then killed at specific intervals with respect to the 13-day cycle of the seminiferous epithelium. PM MWR at 7.7 mW/g (90 min) yielded a modest decline in daily sperm production (DSP) that derived primarily from effects on primary spermatocytes. PM MWR at 4.2 mW/g was ineffective. The mean intratesticular temperature during the former reached 40 degrees C and did not exceed 38 degrees C during the latter. MWR considerably in excess of 7.7 mW/g yielded decrements in virtually all germ cell types, with primary spermatocytes again being most markedly affected. Using conventional heating, intratesticular temperatures in excess of 39 degrees C for 60 min were required for significant decrements in DSP. Levels of circulating follicle-stimulating hormone and of leutinizing hormone were resistant to either treatment. We conclude that the damage threshold and the differential sensitivity of immature germ cells to PM MWR can be adequately explained by the consequent macroscopic heating.
在大鼠中研究了脉冲调制微波辐射（PM MWR，1.3 GHz）和传统加热对睾丸功能的影响。对成年雄性麻醉大鼠（Sprague-Dawley，400-500 g）进行处理，然后在生精上皮13天周期的特定时间点处死。7.7 mW/g的PM MWR（90分钟）使每日精子产量（DSP）适度下降，这主要源于对初级精母细胞的影响。4.2 mW/g的PM MWR无效。前者期间睾丸内平均温度达到40℃，后者期间不超过38℃。远超过7.7 mW/g的MWR几乎使所有生殖细胞类型数量减少，初级精母细胞再次受到最明显影响。使用传统加热时，DSP显著下降需要睾丸内温度超过39℃达60分钟。循环中的促卵泡激素和促黄体生成素水平对这两种处理均有抗性。我们得出结论，随后的宏观加热能够充分解释未成熟生殖细胞对PM MWR的损伤阈值和差异敏感性。
