Blacker C, Cohen J, Castanier M, Debache C, Mandelbaum J, Plachot M, Scholler R
Hum Reprod. 1986 Feb;1(2):69-73. doi: 10.1093/oxfordjournals.humrep.a136363.
178 in-vitro fertilization cycles have been explored for luteal function. Clomiphene and human menopausal gonadotrophins were used for ovarian stimulation and some patients were supplemented with human chorionic gonadotrophin (HCG) (5000 IU) on the day of laparoscopy, and also 2 and 4 days later. An imbalance of luteal function was observed in non-supplemented stimulated cycles, with hyperoestrogenicity and a relatively low production of progesterone. The administration of HCG reduced this imbalance by improving the production of progesterone without affecting the production of oestradiol-17 beta.
对178个体外受精周期的黄体功能进行了研究。使用克罗米芬和人绝经期促性腺激素进行卵巢刺激，部分患者在腹腔镜检查当天以及之后第2天和第4天补充人绒毛膜促性腺激素（HCG）（5000国际单位）。在未补充激素的刺激周期中观察到黄体功能失衡，表现为雌激素过多以及孕酮产生相对较低。HCG的使用通过改善孕酮产生而减少了这种失衡，且不影响雌二醇-17β的产生。
