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情节愈发复杂:类风湿关节炎的一种罕见并发症

When the plot thickens: a rare complication of rheumatoid arthritis.

作者信息

Scheitel Marianne, Ives Samuel T, Nasr Rawad, Nolan Marc W

机构信息

Department of Internal Medicine, Hennepin County Medical Center, University of Minnesota Medical School, Minneapolis, MN, USA.

Division of General Internal Medicine, Hennepin County Medical Center, Minneapolis, MN, USA.

出版信息

J Community Hosp Intern Med Perspect. 2019 Apr 12;9(2):143-146. doi: 10.1080/20009666.2019.1593780. eCollection 2019 Apr.

Abstract

: Rheumatoid arthritis (RA) is a common illness with many extraarticular manifestations. Rheumatoid pachymeningitis is a rare neurologic complication of this common disease. Here in we present a patient with longstanding RA who developed this uncommon complication. : A 75-year-old woman with longstanding RA presented to the clinic with multiple seizure-like spells per day. Upon admission to the hospital, brain MRI showed enhancement of the meninges. After an extensive workup for possible other infectious or inflammatory causes, the patient was diagnosed with rheumatoid pachymeningitis. : Rheumatoid pachymeningitis is a rare complication of RA that usually occurs late in the disease course. It may have many neurologic manifestations include mimicking seizure or stroke and must be considered in patients with RA presenting with neurologic symptoms. Pachymeningitis is treated distinctly from articular RA, so early recognition can lead to appropriate treatment.

摘要

类风湿性关节炎(RA)是一种常见疾病,有许多关节外表现。类风湿性硬脑膜炎是这种常见疾病罕见的神经系统并发症。在此,我们报告一名患有长期类风湿性关节炎且出现这种罕见并发症的患者。:一名患有长期类风湿性关节炎的75岁女性每天出现多次癫痫样发作,前来诊所就诊。入院后,脑部磁共振成像(MRI)显示脑膜强化。在对可能的其他感染或炎症原因进行广泛检查后,该患者被诊断为类风湿性硬脑膜炎。:类风湿性硬脑膜炎是类风湿性关节炎罕见的并发症,通常发生在疾病病程后期。它可能有许多神经系统表现,包括类似癫痫发作或中风,对于出现神经系统症状的类风湿性关节炎患者必须考虑到这种情况。硬脑膜炎的治疗与关节型类风湿性关节炎不同,因此早期识别可导致适当治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f656/6484464/15ee190cc07b/ZJCH_A_1593780_F0001_B.jpg

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