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越南、老挝和柬埔寨的 Zika 病毒:旅行者有健康风险吗?

Zika virus in Vietnam, Laos, and Cambodia: are there health risks for travelers?

机构信息

Institute for Research and Development, Duy Tan University, 03 QuangTrung, Danang, Vietnam.

Vietnam Military Medical University, Hanoi, Vietnam.

出版信息

Eur J Clin Microbiol Infect Dis. 2019 Sep;38(9):1585-1590. doi: 10.1007/s10096-019-03563-6. Epub 2019 May 2.

DOI:10.1007/s10096-019-03563-6
PMID:31044332
Abstract

Vietnam, Laos, and Cambodia have reported first cases of Zika virus (ZIKV) infection since 2010 (Cambodia) and 2016 (Vietnam and Laos). One case of ZIKV-related microcephaly was recognized among a hundred infected cases in these areas, raising a great concern about the health risk related to this virus infection. At least 5 cases of ZIKV infection among travelers to Vietnam, Laos, and Cambodia were recorded. It is noticeable that ZIKV in these areas can cause birth defects. This work aims to discuss the current epidemics of ZIKV in Vietnam, Laos, and Cambodia and update the infection risk of ZIKV for travelers to these areas.

摘要

越南、老挝和柬埔寨自 2010 年(柬埔寨)和 2016 年(越南和老挝)以来首次报告寨卡病毒(ZIKV)感染病例。在这些地区的一百例感染病例中,发现一例寨卡病毒相关小头畸形病例,这引起了对与该病毒感染相关的健康风险的极大关注。至少有 5 例寨卡病毒感染病例记录在前往越南、老挝和柬埔寨的旅行者中。值得注意的是,这些地区的寨卡病毒可导致出生缺陷。本工作旨在讨论越南、老挝和柬埔寨目前的寨卡病毒流行情况,并更新前往这些地区旅行者感染寨卡病毒的风险。

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本文引用的文献

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Evolution of Two Major Zika Virus Lineages: Implications for Pathology, Immune Response, and Vaccine Development.两种主要寨卡病毒谱系的演变:对病理学、免疫反应及疫苗研发的影响
Front Immunol. 2018 Jul 18;9:1640. doi: 10.3389/fimmu.2018.01640. eCollection 2018.
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African and Asian strains of Zika virus differ in their ability to infect and lyse primitive human placental trophoblast.寨卡病毒的非洲和亚洲毒株在感染和裂解原始人胎盘滋养层的能力上有所不同。
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EBioMedicine. 2017 Nov;25:95-105. doi: 10.1016/j.ebiom.2017.10.019. Epub 2017 Oct 20.
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